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同步放化疗在局部晚期鼻咽癌中的应用 被引量：6

Application of synchronic chemotherapy and radiotherapy in treatment of local advanced nasopharyngeal carcinoma
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摘要 鼻咽癌放疗加化疗的综合治疗被公认为最有效的治疗方法,是恶性肿瘤保守治疗的成功典范。由于化疗药物的革新及化疗方案的完善,加之靶向治疗成熟应用于临床,使得肿瘤内科治疗向着高疗效、低毒性方向发展。鼻咽癌放疗与化疗时机的选择成为目前研究的焦点。
作者 杜镭 马林
机构地区 解放军总医院放疗科
出处 《军医进修学院学报》 CAS 2010年第8期829-831,共3页 Academic Journal of Pla Postgraduate Medical School
基金 螺旋断层调强放疗的临床应用研究(Tomotherapy公司 2007.8-2010.7)
关键词 鼻咽肿瘤 放射疗法 综合疗法
分类号 R817.51 [医药卫生—影像医学与核医学]
  • 相关文献

参考文献20

  • 1Hancharek M, Kupelnick B. Combined chemoradiation versus radiation therapy alone in locally advanced nasopharyngeal carcinoma : results of a meta-analysis of 1,528 patients from six randomized trials [ J 1 - Am J Clin Oncol, 2002, 25 ( 3 ) : 219- 223.
  • 2Baujat B, Audry H, Bourhis J, et al. Chemotherapy in locally advanced nasopharyngeal carcinoma : An individual patient data meta-analysis of eight randomized trials and I 753 patients [ J J . Int J Radiat Oncol Biol Phys, 2006, 64 : 47-56.
  • 3杨安奎,刘天润,郭翔,齐国隆,陈福进,郭朱明,张诠,曾宗渊,陈伟超,李秋梨.同步放化疗与单纯放疗在晚期鼻咽癌中疗效比较的Meta分析[J].中华耳鼻咽喉头颈外科杂志,2008,43(3):218-223. 被引量：28
  • 4Langendijk JA, Leemans CR, Buter J, et al. The additional value of chemotherapy to radiotherapy in locally advanced nasopharyngeal carcinoma : a meta-analysis of the published literature [ J ] . J Clin Oncol, 2004, 22 ( 22 ) : 4604-4612.
  • 5Chart AT, Leung SF, Ngan RK, et al. Overall survival after concurrent cisplatin-radiotherapy compared with radiotherapy alone in locoregionally advanced nasopharyngeal carcinoma [ J ] . J Natl Cancer Inst, 2005, 97 : 536-539.
  • 6Lee AW, Lau WH, Tung SY, et al. Preliminary results of a randomized study on therapeutic gain by concurrent chemotherapy for regionally advanced nasopharyngeal carcinoma : NPC-9901 trial by the Hong Kong Nasopharyngeal Cancer Study Group [ J ] . J Clin Oncol, 2005, 23 : 6966-6975.
  • 7Lin JC, Jan JS, Hsu CY, et al. Phase Ⅲ study of concurrent chemoradiotherapy vs. radiotherapy alone for advanced nasopharyngeal carcinoma : Positive effect on overall and progression-free survival[ J ]. J Clin Oncol, 2003, 21 : 631-637.
  • 8Zhang L, Zhao C, Peng PJ, et al. Phase Ⅲ study comparing standard radiotherapy with or without weekly oxaliplatin in treatment of locoregionally advanced nasopharyngeal carcinoma : Preliminary results [ J ] . J Clin Oncol, 2005, 23 : 8461-8468.
  • 9Chitapanarux I, Lorvidhaya V, Kamnerdsupaphon P, et al. Chemoradiation comparing cisplatin versus carboplatin in locally advanced nasopharyngeal cancer : randomised, non-inferiority, open trial [ J ] . Eur J Cancer, 2007, 43 ( 9 ) : 1399-1406.
  • 10Airoldi M, Gabriele AM, Garzaro M, et al. Induction chemotherapy with cysplatin and epirubicin followed by radiotherapy and concurrent cysplatin in locally advanced nasopharyngeal carcinoma observed in a non-endemic population [ J ] . Radiother Oncol, 2009, 92 : 105- ll0.

二级参考文献41

共引文献64

同被引文献39

  • 1蔡永广,符爱珍,劳逸.新辅助化疗联合放疗治疗中晚期鼻咽癌的疗效观察[J].现代肿瘤医学,2007,15(2):187-189. 被引量：7
  • 2张松波,周宏灏.药物代谢性别差异及与核受体的关系[J].中国药理学通报,2007,23(3):292-294. 被引量：23
  • 3孙燕,石远凯.临床肿瘤内科手册[M].北京:人民卫生出版社,2010:329.
  • 4魏素臻,李贵新,王爱红,等.肿瘤预防诊治与康复护理[M].北京:人民军医出版社.2010:105.
  • 5殷蔚伯,余子豪,徐国镇,等肿瘤放射治疗学.第四版[M].北京:中国协和医科大学出版社,2008:1350-1351.
  • 6孙燕,石远凯临床肿瘤内科学手册[M].北京:人民卫生出版社,2007:766.
  • 7Lee N,Harris J,Garden AS,et al. Intensity - modulated radiationtherapy with or without chemotherapy for nasopharyngeal carcino-ma :radiation therapy oncology group phase II trial 0225 [ J]. J ClinOncol,2009,27(22) :3684.
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  • 9Trotti A,Colevas AD,Setser A,et al. CTCAE v3.0:development of a comprehensive grading system for the adverse effects of cancer treatment. Semin Radiat Oncol[J],2003,13:176-181.
  • 10Baujat B,Audry H,Bourhis J,et al. Chemotherapy in locally ad- vanced nasopharyngeal carcinoma:an individual patient data meta-analysis of eight randomized trials and 1753 patients[J]. Int J Rdiat Oncol Biol Phvs,2006.64(l) :47-56.

引证文献6

二级引证文献42

军医进修学院学报
2010年 第8期

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