冠心病与外周动脉硬化的相关性研究

Study of relationship between coronary heart disease and peripheral arteriosclerosis

目的:以超声观测颈动脉(CA)、股动脉(FA)、髂总动脉(CIA)和胸部X线片观测主动脉弓(AA)的动脉硬化(AS),评价其与冠心病(CHD)之间的关联性。方法:对74例冠状动脉造影(CAG)受检者行体表动脉超声及胸部X线片检测,观测CA、FA、CIA及AA的AS,并以此同CAG结果进行比较分析。结果:(1)CHD组病例外周动脉IMT比对照组显著增厚(P<0.05);(2)CHD组与对照组间外周动脉斑块检出率差异显著(P<0.05)。(3)半定量斑块级别增加与冠脉病变增加之间显著相关(P<0.05)。(4)CHD组与对照组间AA钙化检出率差异显著(P<0.05);(5)CA斑块、FA斑块、CIA斑块和AA钙化联合检测来评价CHD的价值高于单独检测。结论:外周动脉AS和AA钙化的检测有助于对CHD的总体评估。胸部X线片可用于检测AA钙化,而高分辨率超声是检测外周动脉AS的有效方法。

Objective：The arteriosclerosis（AS） of carotid artery（CA）,femoral artery（FA）,common iliac artery（CIA） and aortic arch（AA） were observed by ultraso-nography or chest X-ray respectively to evaluate their relationship with coronary heart disease（CHD）.Methods：74 cases undergoing coronary angiography（CAG） were checked by ultrasonography and chest X-ray respectively to observe the case of AS of CA,FA,CIA and AA,which were analyzed with the results of CAG.Results：（1） Intima-media thickness（IMT） of peripheral arteries of cases in CHD group were more thickened than the ones in control group significantly（P 0.05）.（2） Proportions of AS plaques detected in peripheral arteries were significantly different between CHD group and control group（P 0.05）.（3） Semiquantitative AS plaque classification increased with the number of stenosed coronary branches（P 0.05）.（4） Proportions of objects with AA calcification between CHD group and control group were significantly different（P 0.05）.（5） CHD was evaluated by CA plaque,FA plaque,CIA plaque and AA calcification jointly had greater value than respectively.Conclusions：Peripheral arterial AS and AA calcification contribute to the overall evaluation of CHD.Chest X-ray can be used to detect AA calcification,while high-resolution ultrasonography is an effective meth-od for the detection of peripheral AS.