肿瘤化疗与免疫疗法联合应用新进展

Progress in tumor combination treatment of chemotherapy and innnunotherapy

目前应用于恶性肿瘤的治疗方法主要有手术治疗、放疗、化疗以及免疫治疗等。虽然这些方法对肿瘤有一定的治疗作用，但应用单一的治疗手段均有不同的局限性，因此人们不断寻求多种治疗方法的联合应用，以期达到更好地抑制肿瘤生长及改善患者预后的效果。在已探索的各种化疗和免疫治疗的组合中，化疗联合细胞因子、化疗联合肿瘤疫苗、化疗联合免疫佐剂等组合在各种试验及临床应用中均取得可喜效果，有望为人们攻克肿瘤这一难题提供新的途径。

Methods involved in the treatment of malignant tumor are surgical therapy, radiotherapy, chemotherapy and immunothcrapy. Although some effects have been showed in tumor therapy, the limits of single use of those methods can not be avoided. Therefore, combined therapy has been pursued in order to achieve better results. The effects of those combined methods such as chemotherapy combined with cytokine, chemotherapy combined with tumor vaccine, chemotherapy combined with adjuvants have been approved both experimentally and clinically. These results, in some extent, will provide us a new way to fight against tumor.