贲门癌的临床病理特征分析

Clinicomathological characteristics of gastric cardia cancer

目的:探讨贲门癌与胃远端癌之间临床病理因素的差异及临床意义。方法:回顾性分析2001-01-2001-12天津医科大学肿瘤医院手术治疗,经病理确诊且随访资料完整的100例贲门癌患者和130例胃远端癌患者。结果:贲门癌与胃远端癌在发病年龄、性别、肿瘤大小、以及侵犯深度上差异有统计学意义,P<0.05。贲门癌平均最大直径5.82cm,胃远端癌平均最大直径4.71cm,P<0.05;贲门癌T3和T4为90例(90.0%),胃远端癌109例(83.8%),P<0.05。贲门癌患者根治术后5年生存率为41.9%。结论:贲门癌的临床病理特征与胃远端癌存在差异,根治术可以提高患者的生存期。

OBJECTIVE：To investigated patients with carcinoma of the gastric cardia in order to evaluate the defference between carcinoma of cardia and the distal third gastric carcinoma from Jan.2010 to Dec.2010 in Tianjin Cancer Hospital.METHODS：A total of 100 patients were diagnosed with carcinoma of cardia and compared with findings on 130 patients with tumors in distal third gastric carcinoma.RESULTS：It showed difference in age,sex,size and invasion（P〈0.05）.Tumors of the cardia had a mean size of 5.82 cm,which was significantly larger than the mean size of 4.71 cm for tumors found in the distal third gastric carcinoma（P〈0.05）.T1 and T2 stage tumors were less common in patients with carcinoma（n=90,90.0%）of cardia than in those with distal third gastric carcinoma（n=109,83.8%,P〈0.05）.When the carcinoma of cardia group was underwent resection,the 5-year survival rates were 41.9%.CONCLUSIONS：Carcinoma of cardia has its own clinical characteristics.According to our results,radical resection itself,rather than tumor location,is the determining factor in improving survival.