子宫内膜异位症腹腔镜手术后辅助散结镇痛胶囊治疗的疗效分析

Clinical observation of treatment in endometriosis with sanjiezhentong capsule after laparoscopic surgery

目的 研究子宫内膜异位症经腹腔镜手术后辅助散结镇痛胶囊治疗的疗效.方法 将33例腹腔镜手术的子宫内膜异位症患者按自愿原则分为两组：散结镇痛胶囊组（19例）,合并不孕9例;戈舍瑞林（诺雷得）组14例,合并不孕8例.两组患者分别于手术后首次月经来潮第1天开始给予相应药物治疗3个月,治疗后比较两组疗效、不良反应及受孕情况.结果 散结镇痛胶囊组总有效率为73.7%（14/19）,合并不孕者受孕率为55.6%（5/9）;诺雷得组分别为78.6%（11/14）、62.5%（5/8）,两组比较差异均无统计学意义（P〉0.05）.散结镇痛胶囊组不良反应发生率显著低于诺雷得组.结论 散结镇痛胶囊用于子宫内膜异位症腹腔镜术后的辅助治疗是有效的,且不良反应小.

Objective To evaluate the efficacy of laparoscopic surgery combined with sanjiezhentong capsule for endometriosis. Methods Thirty-three cases of endometriosis who accepted conservative surgery were divided into 2 groups： 19 cases accepted treatment of sanjiezhentong capsule （sanjiezhentong capsule group, infertile patients were 9 cases） and 14 cases accepted goserelin （goserelin group, infertile patients were 8 cases ）. The treatment of two groups were given drugs on the first day of menstrual onset after operation for 3 months. The effect, side effect and pregnant was compared after treatment. Results The total effective rate of sanjiezhentong capsule group was 73.7%（ 14/19） and in goserelin group was 78.6%（ 11/14）, there had no statistically significant （P〉 0.05）. The pregnancy rate of secondary infertile patients in sanjiezhentong capsule group was 55.6%（5/9） and in goserelin group was 62.5%（5/8）（P〉 0.05）. The side effect was lower in sanjiezhentong capsule group than that in goserelin group. Conclusion Sanjiezhentong capsule is a safe and effective drug in treating post-operative endometriosis.