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神经母细胞瘤骨髓转移17例骨髓象及临床表现分析 被引量:1

Analysis of Bone marrow Smear and clinical performance in 17 cases bone marrow metastasis neuroblastoma
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摘要 目的探讨神经母细胞瘤骨髓转移骨髓象及临床表现特征。方法对17例神经母细胞瘤骨髓转移患者的骨髓象及临床检查进行分析。结果本组神经母细胞瘤最常见的原发部位为腹部,其次位于后纵隔,多以贫血或全血细胞减少为首发表现。骨髓转移神经母细胞瘤形态多样,本组主要为淋巴细胞型、粒细胞型。结论骨髓细胞形态学既可确定诊断,又可观察疗效,骨髓穿刺应为首选检查方法。 Objective To investigate the bone marrow metastasis of neuroblastoma and clinical performance characteristics. Methods To analyse 17 cases of neurobhstoma bone metastasis and clinical examination. Results Neuroblastoma in this groupthemost eommonprnnary site in the abdomen,followed in the posterior mediastinum, anemia or pancytopemaare initial manifestations. The modality of Bone marrow metastasis are vailous, most are lymphocyte type and granulocyte cell type. Conclusion The morphology of bone marrow cells can confirm the diagnosis, but also observe the efficaey. Bone marFow smear should be the preferred screening method.
出处 《医学检验与临床》 2010年第3期47-48,共2页 Medical Laboratory Science and Clinics
关键词 神经母细胞瘤 骨髓转移 Neuroblastoma Bone marrow metastasis
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  • 1杨学农,杨晓荣,郑晓萌,李顺义.成年入神经母细胞瘤骨髓转移一例[J].中华检验医学杂志,2007,30(6):705-705. 被引量:1
  • 2Maris JM, Hogarty MD, Bagatell R, et al. Neuroblastoma [ J ].Lancet,2007,369(9579) :2106-2120.
  • 3Brodeur GM, Maris JM. Neuroblastoma. In: Pizzo PA, PoplackDG. Principles and practice of pediatric oncology [ M ]. 5th ed.Philadelphia: Lippincott Williams & Wilkins,2006:933-970.
  • 4Granchi D, Corrias MV,Garaventa A,et al. Neuroblastoma andbone metastases : clinical significance and prognostic value ofDickkopf 1 plasma levels [ J ]. Bone,2011,48:152-159. doi : 10,1016/j. bone. 2010.06.028.
  • 5Sorrentino S, Rosanda C, Parodi S, et al. Cyto-morphologicevaluation of bone marrow in infants with disseminatedneuroblastoma[ J]. J Pediatr Hematol Oncol, 2012,34 ( 2 ) : 154-158. doi: 10.1097/MPH.0b013e31821d80be.
  • 6Matthay KK, Villablanca JG,Seeger RC, et al. Treatment ofhigh-risk neuroblastoma with intensive chemotherapy,radiotherapy,autologous bone marrow transplantation,and 13 -cis-retinoic acid. Children's Cancer Group[ J]. N Engl J Med,1999 ,341(16) :1165-1173.
  • 7肖晓光.成人肾上腺神经母细胞瘤骨髓转移1例报告[J].吉林医学,2010,31(26):4623-4624. 被引量:1

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