健脾疏肝消糖散治疗葡萄糖耐量低减24例总结

A Summary on 24 Cases of Impaired Glucose Tolerance Treated by Jianpi Shugan Xiaotang Powder

目的:观察健脾疏肝消糖散治疗葡萄糖耐量低减(IGT)的临床疗效。方法:将确诊为IGT的患者66例随机分为生活干预组(干预组)22例、二甲双胍组(西药组)20例、中药加二甲双胍组(中西药组)24例,3组患者均给予生活干预,西药组给予盐酸二甲双胍治疗,中西药组给予健脾疏肝消糖散及盐酸二甲双胍治疗。结果:治疗前后比较,3组空腹血糖及餐后血糖水平均有下降(P<0.05或P<0.001),中西药组及西药组空腹血糖、餐后血糖下降较为明显(P<0.001);3组患者治疗前后TG、TC变化比较,干预组TG、TC水平下降不明显(P>0.05);而中西药组TG、TC降低较为明显(P<0.05或P<0.001);西药组TG下降不明显(P>0.05),TC降低较为明显(P<0.05);3组治疗前后体重指数(BMI)下降不明显(P>0.05)。结论:通过生活干预、服用健脾疏肝消糖散及盐酸二甲双胍均可改善IGT患者的血糖水平;中药健脾疏肝消糖散能够改善空腹、餐后血糖水平及血脂水平,可以有效地治疗IGT。

Objective： To observe the clinical effect on impaired glucose tolerance treated by Jianpi Shugan Xiaotaog powder. Method： 66 cases were randomly divided into 22 cases in the living intervention group, 22 cases in the western therapy group and 24 cases in the integrated Chinese traditional and western medicine group. Three groups all gave living intervention therapy. Cases in the western therapy group treated by dianoguanil, cases in the integrated Chinese traditional and western medicine group treated by Jianpi Shugan Xiaotang powder and dianoguanil. Results ： The blood - fasting sugar and postprandial blood sugar decreased in the three groups after treatment（P 〈0.05 or P 〈0. 001 ）. The blood -fasting sugar and postprandial blood sugar decreased markedly in the western therapy group and in the integrated Chinese traditional and western medicine group（ P 〈 0. 001 ）. The level of TG and TC had no significant difference in the living intervention group after treatment（ P 〉 0.05 ） , the level of TG and TC had significant difference in the integrated Chinese traditional and western medicine group after treatment （ P 〈 0.05 or P 〈 0. 001 ）, the level of TG had no significant difference（ P 〉 0.05 ） but level TC had significant difference in the western therapy group after treatment（ P 〈 0.05 ）. BMI did not decreased markedly in the three groups after treatment（P 〉 0.05）. Conclusion： Living intervention therapy, Jianpi Shugan Xiaotang powder and dianoguanil could improve blood sugar level it/patients with impaired glucose tolerance. Jianpi Shugan Xiaotang powder could improve blood -fasting sugar, postprandial blood sugar and blood -fat, so it was effective for treating impaired glucose tolerance.