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慢性粒细胞白血病相关microRNA的研究进展 被引量：3

Research advances on chronic myeloid leukemia-related microRNA
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摘要 微小RNA(microRNA)是一组片段短小但功能丰富,序列高度保守,表达具有时序性和组织特异性的核苷酸序列。近年来通过对microRNA生物学功能的研究发现,microRNA在细胞的生长、分化、凋亡以及肿瘤的发生、转移、耐药等过程中发挥重要作用。microRNA与血液系统疾病的关系也在逐渐被阐明,本文就慢性粒细胞白血病相关microRNA的研究进展做一综述。 microRNAs （miRNAs） are a group of short fragments with rich feature. They have highly conserved sequences, timing and tissue-specific expression, miRNAs plays an important role in cell growth, differentiation and apoptosis, and also in tumor generation, metastasis and drug-resistance, miRNAs associated with leukemia have also been reported. In this review, we summarize the recent progress about miRNAs in chronic myeloid leukemia.
作者 刘静 王小中
机构地区 南昌大学第二附属医院检验科
出处 《分子诊断与治疗杂志》 2010年第4期280-283,共4页 Journal of Molecular Diagnostics and Therapy
基金 国家自然科学基金(30700338)
关键词 微小RNA 慢性粒细胞白血病 microRNA Chronic myelocytic leukemia
分类号 R733.72 [医药卫生—肿瘤]
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参考文献20

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同被引文献31

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分子诊断与治疗杂志
2010年 第4期

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