斋月前后糖尿病代谢指标的变化

Changes of metabolic index of diabetes before and after Ramadan

目的 研究斋月前后糖尿病糖脂代谢指标的变化.方法 选择65名资料完整的斋戒穆斯林糖尿病患者,调查斋戒前后饮食、用药情况及是否有低血糖事件出现,对检测体重（WEIGHT）、腰围（WAISTLINE）、体重指数（BMI）、空腹血糖（FPG）、餐后2 h血糖（2 h-PG）、糖化血红蛋白（HbA1c）、胆固醇（TG）、甘油三脂（TC）、高密度脂蛋白胆固醇（HDL-C）、低密度脂蛋白胆固醇（LDL-C）等指标进行评价.结果 斋戒组斋月期间脂肪及蛋白质摄入明显增加（P＜0.01）,空腹时间明显延长（P＜0.01）,斋月后2h-PG、HbA1c明显升高（P=0.0149,0.0175）.WEIGHT、WAISTLINE、BMI、TG、TC、HDL-C、LDL-C及低血糖事件无明显差异.对照组血糖指标有明显改善.结论 斋戒组斋戒期间生活方式变化较大,血糖控制不良.

Objective To investigate changes of metabolism of glucose and lipoids in diabetes before and after Ramadan. Methods A total of 65 Muslim fasting diabetic patients, with complete data, were investigated about their diet and administrated medicines before and after the fasting and occurrence of hypoglycemia during the fasting. Indexes of WEIGHT, WAISTLINE, BMI, FPG, 2h-PG, HbA1c, TG, TC, HDL-C, and LDL-C were evaluated by questionnaire, physical examination and laboratory tests. Results During Ramadan, fasting time was prolonged （P＜0.01）, intake of lipoids and protein were increased obviously （P＜0.01） and a significant increase of 2 h-PG, HbA1c （P=0.0149, 0.0175） was detected after Ramadan in s fasting group. No significant difference was found in WEIGHT, WAISTLINE, BMI, TG, TC, HDL-C, and LDL-C. Blood glucose was improved significantly in the control group than the fasting group. Conclusion Life style was changed obviously leading to unsatisfactory controlling of blood glucose in Muslim diabetic patients during Ramadan.