银杏叶滴丸的制剂工艺研究

Study on preparation process for Yinxingye Dropping Pills

目的 建立银杏叶滴丸的最佳成型工艺.方法 采用正交试验法,从基质、冷却剂的种类、提取物与基质的用量配比等方面进行考察.结果 提取物聚乙二醇-600为1：3,滴制温度为70℃,滴速为30滴/min,滴距为8 cm,冷却温度10℃时,银杏叶滴丸质量最好.结论 该工艺适用于滴丸实验室试验和工业化生产.

Objective To establish the optimum preparation process for Yinxingye Dropping Pills. Methods The preparation conditions, such as different kinds of primary substance, cooling agent, the proportion between the extracts and primary substance, etc, were studied with L9 （34） orthogonal design. Results At the following conditions could the best quality of Yinxingye Dropping Pills be gotten： polyglycol-6000 was 1 ： 3, dropping temperature was 70℃, dropping speed was 30 d/min, dropping distance was 8cm, and cooling temperature was 10℃. Conclusion This preparation process was suitable for both laboratory test and industrial production for Yinxingye Dropping Pills.