期刊文献+

Th17细胞与肝脏疾病 被引量:3

下载PDF
导出
摘要 Th17细胞是一类独立于Th1(T helper type1)、Th2的CD4+Th细胞亚群,在其分化过程中需要白细胞介素6(interleu-kin6,IL-6)和转化生长因子β(transforming growth factorβ,TGF-β)、IL-23、转录因子ROR-γt(orphan nuclear hormone re-ceptor-γt)及STAT3(signal transducer and activator of transcription3)参与。
出处 《河北医药》 CAS 2010年第15期2096-2099,共4页 Hebei Medical Journal
  • 相关文献

参考文献22

  • 1Krakowski M,Owens T.Interferon-γ confers resistance to experimental allergic encephalo-myelitis.J Immunol,1996,26:1641-1646.
  • 2Veldhoen M,Hocking RJ,Atkins CJ,et al.TGF beta in the context of an inflammatory cytokine milieu supports denovo differentiation of IL-17-producing T cells.Immunity,2006,24:179-189.
  • 3Yang XO,Panopoulos AD,NurievaR,et al.STAT3 regulates cytokine-mediated generation of inflammatory helper T cells.J Biol Chem,2007,282:9358-9363.
  • 4Cua DJ,Sherlock J,Chen Y,et al.Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain.Nature,2003,421:744-748.
  • 5Weaver CT,Harrington LE,Mangan PR,et al.Th17:An effector CD+4T cell lineage with regulatory T cell Ties.Immunity,2006,24:677-688.
  • 6Harrington LE,Hatton RD,Mangan PR,et al.Interleukin 17-producing CD4 effector T cells develop via a liesge distinct from the T helper type 1 and lineages.Nat Immunol,2005,6:1123-1132.
  • 7Wahl SM,Wen J,Moutso P.TGF-beta:a mobile purveyor of immune privilege.Immunol Rev,2006,213:213-217.
  • 8Batten M,Li J,Yi S,et al.Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin17-producing T cells.Nat Immunol,2006,7:929-936.
  • 9Bettelli E,Oukka M,Kuchroo VK.TH-17 cells in the circle of immunity and autoimmunity.Nature Immunology,2007,8:345-350.
  • 10Ivanov II,Mckenzie BS,Zhou L,et al.The orphan nuclear receptor ROR-rt directs the differenttiation program of proinflammatory IL-17+ T helper cells.Cell,2006,126:1121-1133.

同被引文献20

  • 1Ying-Hua Niu,Dong-Lin Yin,Hong-Li Liu,Rui-Tian Yi,Yu-Cong Yang,Hong-An Xue,Tian-Yan Chen,Shu-Lin Zhang,Shu-Mei Lin,Ying-Ren Zhao.Restoring the Treg cell to Th17 cell ratio may alleviate HBV-related acute-on-chronic liver failure[J].World Journal of Gastroenterology,2013,19(26):4146-4154. 被引量:35
  • 2Jian Ge,Kai Wang,Qing-Hua Meng,Zhao-Xia Qi,Fan-Li Meng,Yu-Chen Fan.Implication of Th17 and Th1 Cells in Patients with Chronic Active Hepatitis B[J].Journal of Clinical Immunology.2010(1)
  • 3Pitta MG,,Romano A,Cabantous S,et al.IL-17 and IL-22 are associated with protection against human kala azar caused by Leishmania donovani[].The Journal of Clinical Investigation.2009
  • 4Zheng Y,Danilenko DM,Valdez P,et al.Interleukin-22,a T(H)17cytokine,mediates IL-23-induced dermal inflammation and acanthosis[].Nature.2007
  • 5Zenewicz LA,Yancopoulos GD,Valenzuela DM et al.Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation[].Immunity.2007
  • 6Witte E,Witte K,Warszawska K,et al.Interleukin-22:a cytokineproduced by T,NK and NKT cell subsets,with importance in the in-nate immune defense and tissue protection[].Cytokine and Growth Factor Reviews.2010
  • 7Pitta MG,,Romano A,Cabantous S,et al.IL-17 and IL-22 are associated with protection against human kala azar caused by Leishmania donovani[].The Journal of Clinical Investigation.2009
  • 8Zheng Y,Danilenko DM,Valdez P,et al.Interleukin-22,a T(H)17cytokine,mediates IL-23-induced dermal inflammation and acanthosis[].Nature.2007
  • 9Zenewicz LA,Yancopoulos GD,Valenzuela DM et al.Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation[].Immunity.2007
  • 10Witte E,Witte K,Warszawska K,et al.Interleukin-22:a cytokineproduced by T,NK and NKT cell subsets,with importance in the in-nate immune defense and tissue protection[].Cytokine and Growth Factor Reviews.2010

引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部