舒芬太尼在无痛胃镜检查中的应用

Application of Sufentanil in Painless Gastroscopy

目的探讨舒芬太尼复合丙泊酚在无痛胃镜检查中的麻醉效果。方法选取200例ASAⅠ～Ⅱ级,年龄18～54岁,进行上消化道内镜检查的患者,随机分成Ⅰ组(芬太尼组)和Ⅱ组(舒芬太尼组),每组100例。Ⅰ组芬太尼1μg/kg+丙泊酚1mg/kgiv,Ⅱ组舒芬太尼0.1μg/kg+丙泊酚1mg/kgiv,观察NBP、HR、SPO2、丙泊酚用量、苏醒时间、体动以及心动过缓等术中并发症的发生率。结果Ⅱ组的丙泊酚用量较Ⅰ组显著减少(P<0.05),Ⅱ组的苏醒时间较Ⅰ组显著缩短(P<0.05),两组的术中并发症的发生率差异无统计学意义(P>0.05)。结论 0.1μg/kg舒芬太尼复合1mg/kg丙泊酚适用于无痛胃镜检查术。

Objective To investigate curative effects of sufentanil combined with propofol in painless gastroscopy.Methods 200 cases of ASA（Grade Ⅰ-Ⅱ,8～54 years-old）undergoing painless gastroscopy were randomly divided into 2 groups：Group I（1 μg /kg fentany1 ＋ 1 mg /kg iv of propofol,n=100）and groupⅡ（sufentanil 0.1 μg /kg ＋ propofol 1 mg /kg,n=100）.The following paratmeters were monitored：NBP,HR and SPO2 during operation,dosages of propofol,revival time,and operative side effects such as the body movement and bradycardia.Results Dosages of propofol in Group II were significantly lower than that in group I（P〈0.05）.Revival time in Group II was significantly shorter than that in group I（P〉0.05）.No significant difference（P〈0.05）was observed between groupⅠand groupⅡ in terms of the incidence of operative side effects.Conclusion Combined sufentanil（0.1 μg /kg）and propofol（1 mg /kg）are optimal doses in painless gastroscopy