108例反复呼吸道感染患儿体液免疫及细胞免疫功能测定分析

Determination and analysis of humoral immune and cellular immune function of 108 children with recurrent respiratory infection

目的探讨反复呼吸道感染患儿血清免疫球蛋白、外分泌液ＳＩｇＡ及外周血淋巴细胞转化率的改变，评价其免疫功能。方法血清免疫球蛋白、Ｃ３，采用免疫比浊法；唾液ＳＩｇＡ采用火箭电泳法；外周血淋巴细胞转化率测定采用３Ｈ－ＴｄＲ渗入法。结果反复呼吸道感染患儿血清ＩｇＧ、ＩｇＡ显著低于正常；外分泌液ＳＩｇＡ水平及外周血淋巴细胞转化率也较正常显著降低。结论反复呼吸道感染患儿存在体液免疫和细胞免疫功能的降低。

Objectives To study the changes of humoral immune and cellular immune functions of children with recurrent respiratory infection(RRI).Methods serum immunogloblins and C 3 were examined in immunonephelometry SIgA content in saliva was assayed by rocket immunoelectrophoresis. LTT was assayed by 3 H-TdR incorporation method.Results IgG、IgA and IgM content in serum, SIgA content in saliva and LTT of children with RRI were lower than that of control group( P <0.05).Conclusion Children with RRI have lower humoral immune and cellular immune function