摘要
目的探讨反复呼吸道感染患儿血清免疫球蛋白、外分泌液SIgA及外周血淋巴细胞转化率的改变,评价其免疫功能。方法血清免疫球蛋白、C3,采用免疫比浊法;唾液SIgA采用火箭电泳法;外周血淋巴细胞转化率测定采用3H-TdR渗入法。结果反复呼吸道感染患儿血清IgG、IgA显著低于正常;外分泌液SIgA水平及外周血淋巴细胞转化率也较正常显著降低。结论反复呼吸道感染患儿存在体液免疫和细胞免疫功能的降低。
Objectives To study the changes of humoral immune and cellular immune functions of children with recurrent respiratory infection(RRI).Methods serum immunogloblins and C 3 were examined in immunonephelometry SIgA content in saliva was assayed by rocket immunoelectrophoresis. LTT was assayed by 3 H-TdR incorporation method.Results IgG、IgA and IgM content in serum, SIgA content in saliva and LTT of children with RRI were lower than that of control group( P <0.05).Conclusion Children with RRI have lower humoral immune and cellular immune function
出处
《宁夏医学杂志》
CAS
1999年第3期142-143,共2页
Ningxia Medical Journal
关键词
呼吸道感染
体液免疫
细胞免疫
反复感染
儿童
Recurrent respiratory infection
Humoral immune function
Cellular immune function
Secretory IgA