摘要
目的:评估血清BuChE活性和PA、Alb浓度在肝硬化诊断和治疗中的价值。方法:测定197例肝硬化患者血清BuChE活性和PA、Alb浓度,计算出BuChE、PA和Alb诊断肝硬化的各项性能指标。结果:肝硬化患者血清BuChE活性、PA和Alb浓度明显低于对照组(P<0.01),并且在Child-Pough各级之间及各级和对照组之间的差异有显著性意义(P<0.01),肝硬化患者总体血清BuChE活性和PA浓度与血清Alb浓度呈显著正相关。结论:血清BuChE和PA在肝硬化的诊断和疗效观察方面比Alb具有更多的优点。
Objective: To evaluate the clinical values of BuChE and PA and Alb Assay in diagnosis and prognosis of cirrhosis. Methods: To measure the activity of BuChE and the concentration of PA and Alb in serum of 197 patients with cirrhosis.The sensitivity and specificity and other performances of BuChE and PA and Alb assay for the detection of cirrhosis were evaluated by ROC curve analysis. Results: The activity of BuChE and the concentration of PAand Alb in serum of 197 patients with cirrhosis are lower than the control group( P 〈 0.01). There are singnificant difference between Child - Pough A and Child - Pough B Child - Pough C, each grade and the control group( P 〈 0.01 ). The activity of BuChE and concentration of PA are positive correlation to the concentration of Alb in the patients with cirrhosis. Conclusions: The serum BuChE and PA are better than Alb in the diagnosis and prognosis of cirrhosis.
出处
《内蒙古中医药》
2010年第11期132-133,共2页
Inner Mongolia Journal of Traditional Chinese Medicine