肝硬化患者血清内皮素和单胺氧化酶变化的临床意义

Evaluation Serum ET and MAO of Testing in Detecting Liver Cirrhosis

目的:分析不同时期肝硬化患者血清内皮素(ET)和单胺氧化酶(MAO)浓度的变化,确定血清ET和MAO的变化和肝硬化关系。方法:用放射免疫分析法检测92例肝硬化患者血清ET同时用快速比色发检测血清MAO与对照组40名健康者血清ET和MAO比较。结果:肝硬化组血清ET和MAO和对照组之间差别均有统计学意义(P<0.01),在肝硬化的不同组之间血清ET和MAO之间差别也具有统计学意义(P>0.05)。结论:联合检测检测血清ET和MAO对了解肝硬化患者病情和预后评估具有临床价值。

Objective To discuss the significance of ET and MAO in patients with liver cirrhosis. Methods： Immunoturbidimetry assay was applied to measuring ET and measuring MAO. Resuh： Serum ET and MAO was significantly elevated in liver cirrhosis （ P 〈 0.01 ）. Serum ET and MAO has difference between two groups of liver cirrhosis （P 〈 0.05） Conclusions：Measuring serum ET and MAO can reflect the condition and prognosis in patients with liver cirrhosis.