细胞减灭术加腹腔热灌注化疗治疗腹膜转移癌的动物实验研究进展
摘要
腹盆腔恶性肿瘤局域性进展形成腹膜转移癌(peritoneal carcinomatosis,PC),中位生存期不足6个月。细胞减灭术(cytoreductive surgery,CRS)联合腹腔热灌注化疗(hyperthermic intraperitoneal chemotherapy,HIPEC)综合了手术、区域化疗、热疗和大容量液体的灌洗作用,术中清除游离癌细胞和微癌灶,是目前治疗PC的先进方法。
出处
《医学新知》
CAS
2010年第3期174-178,共5页
New Medicine
基金
基金项目:教育部“国家大学生创新性实验计划”国家重点项目(编号:081048646)
参考文献32
-
1Jayne D G,Fook S,Loi C,et al.Peritoneal carcinomatosis from colorectal cancer[J].Br J Surg,2002,89(6):1545-1550.
-
2Yang X J,Li Y,Hassan A H A,et al.Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy improves survival in selected patients with peritoneal carcinomatosis from abdominal and pelvic malignancies:results of 21 cases[J].Ann Surg Oncol,2009,16(2):345-351.
-
3Pilati P,Mocellin S,Rossi C R,et al.Cytoreductive surgery combined with hyper-thermic intraperitoneal intraoperative chemotherapy for peritoneal carcino-matosis arising from colon adenocarcinoma[J].Ann Surg Oncol,2003,10(5):508-513.
-
4李雁(综述),杨国梁(综述),杨肖军(审校).细胞减灭术加腹腔热灌注化疗治疗腹膜种植瘤的研究进展[J].中国肿瘤临床,2007,34(21):1257-1260. 被引量:20
-
5Piso P,Dahlke M H,Ghali N,et al.Multimodality treatment of peritoneal carcinomatosis from colorectal cancer:?rst results of a new German centre for peritoneal surface malignancies[J].Int J Colorectal Dis,2007,22:1295-300.
-
6Yan T D.Peritoneal carcinomatosis of colorectal origin:standard of care[J].Ann Surg,2006,244:632-633.
-
7Bae J H,Lee J M,Ryu K S,et al.Treatment of ovarian cancer with paclitaxel-or carboplatin-based intraperitoneal hyperthermic chemotherapy during second surgery[J].Gyn Oncol,2007,106:193-200.
-
8Yonemura Y,Ikeno T,Shinbo M,et al.Long-term results of peritonectomy on the patients with peritoneal carcinomatosis[J].Gan To Kagaku Ryoho,2007,34:1926-1930.
-
9Wang G P,Guan Y S,Jin X R,et al.Development of novel 5-fluorouracil carrier erythrocyte with pharmacokinetics and potent antitumor activity in mice bearing malignant ascites[J].J Gastroen Hepatol,2010,25:985-990.
-
10Kulu Y,Dorfman J D,Kuruppu D,et al.Comparison of intravenous versus intraperitoneal administration of oncolytic herpes simplex virus 1 for peritoneal carcinomatosis in mice[J].Cancer Gene Ther,2009,16:291-297.
二级参考文献46
-
1高枫,陈利生,唐宗江,张志勇,刘小健.术中腹腔内温热灌注化疗联合治疗中晚期大肠癌[J].中华实验外科杂志,1995,12(3):151-152. 被引量:19
-
2Los G,Smal OA,van Vugt MJ,et al.A rationale for carboplatin treatment and hyperthermia in cancers restricted to the peritoned cavity[J].Cancer Res,1992,52(2):1252-1258.
-
3Glehen O,Stuart OA,Mohamed F,et al.Hyperthermia modifies pharmacokinetics and tissue distribution of intraperitoneal melphalan in a rat model[J].Cancer Chemother Pharmacol,2004,54(1):79-84.
-
4Pelz JO,Doerfer J,Hohenberger W,et al.A new survival model for hyperthermic intraperitoneal chemotherapy (HIPEC) in tumor-bearing rats in the treatment of peritoneal carcinomatosis[J].BMC Cancer,2005,5:56.
-
5Blazick S,Rovensky J,Koska J,et al.Effect of hyperthermic water bath on parameters of cellular immunity[J].Int J Clin Pharmacol Res,2000,20(1-2):41-46.
-
6Glehen O, Schreiber V, Cotte E, et al. Cytoreductive surgery and intraperitoneal chemohyperthermia for peritoneal carcinomatosis arising from gastric cancer. Arch Surg, 2004,139( 1 ) :20-26.
-
7Glehen O, Cotte E, Schreiber V, et al. Intraperitoneal chemohyperthermia and attempted cytoreductive surgery in patients with peritoneal carcinomatosis of colorectal origin. Br J Surg, 2004,91 (6) :747-754.
-
8Glehen O, Kwiatkoski M, Sugarbaker PH, et al. Cytoreductive surgery combined with perioperative intraperitoneal chemotherapy for the management of peritoneal carcinomatosis from colorectal cancer. A multi-institutional study. J Clin Oncol, 2004,22 (16) :3284-3292.
-
9Verwaal VJ, van Ruth S, de Bree E, et al. Randomized trial of cytoreduction and hyperthermic intraperitoneal chemotherapy versus systemic chemotherapy and palliative surgery in patients with peritoneal carcinomatosis of colorectal cancer. J Clin Oncol, 2003,21 ( 20 ) : 3737- 3743.
-
10Verwaal VJ, van Ruth S, Witkamp A, et al. Long-term survival of peritoneal carcinomatosis of colorectal origin. Ann Surg Oncol, 2005, 12( 1 ) :65-71.
共引文献29
-
1张亮,王亚非.腹腔热灌注联合静脉化疗对消化道肿瘤的效果观察[J].南通医学院学报,2004,24(4):486-486.
-
2杨兴华,方明治,徐伟,黄欣,毛琰涛,朱翔,李敏.热疗联合静脉及腹腔双路化疗治疗晚期胃肠道肿瘤临床观察[J].现代肿瘤医学,2008,16(12):2144-2146. 被引量:8
-
3刘都户,刘文超,喻召才,范黎,朱延光,盛蓉,薛妍,黄颖.体外循环体腔热灌注顺铂治疗浆膜腔恶性积液的临床观察[J].中华肿瘤防治杂志,2009,16(5):381-383. 被引量:12
-
4梅列军,杨肖军,李雁,杨国梁.兔VX2腹膜转移癌模型的建立及转移特征研究[J].中国肿瘤临床,2009,36(9):523-526. 被引量:4
-
5王宁,杨肖军,李雁.细胞减灭术联合腹腔热灌注化疗治疗腹膜转移癌患者的护理[J].护理学杂志(外科版),2009,24(9):33-34.
-
6侯琳,刘元春,宋玲,何美玲.卵巢癌减灭手术同期腹腔热灌注化疗的手术配合[J].中华护理杂志,2009,44(12):1114-1115. 被引量:4
-
7詹宏杰,梁寒,王宝贵,邓靖宇,郝希山.60例进展期胃癌术中腹腔热灌注化疗的临床观察[J].中国肿瘤临床,2010,37(4):229-231. 被引量:19
-
8杨肖军,杨国樑,李雁,卢玉兰,刘少阳,张京伟,陈良冬.细胞减灭术加腹腔热灌注化疗治疗腹膜癌[J].武汉大学学报(医学版),2010,31(2):192-196. 被引量:1
-
9刘涛,郝英祥,王化改.胃肠道恶性肿瘤术后的腹腔化疗[J].中国医学创新,2010,7(9):101-102. 被引量:2
-
10任金香,王凤展,史雪前.顺铂腹腔热灌注联合吉西他滨静脉化疗治疗卵巢癌恶性腹腔积液的临床观察[J].山西医药杂志(上半月),2010,39(6):531-532. 被引量:7
-
1王亚华,张薇,何莉.腹腔热灌注化疗治疗恶性腹水的观察与护理[J].基层医学论坛(B版),2006,10(11):1041-1042. 被引量:1
-
2张新民,唐震,梁青春.甲状腺乳头状癌VEGF-C、VEGFR-3的表达及意义[J].实用预防医学,2005,12(6):1291-1292. 被引量:1
-
3王俞,崔书中,巴明臣,吴印兵,唐鸿生.细胞减灭术联合腹腔热灌注化疗在恶性肿瘤治疗中的应用[J].实用医学杂志,2013,29(15):2574-2577. 被引量:7
-
4唐鸿生,崔书中,唐云强,巴眀臣,吴印兵,张相良.腹腔热灌注化疗治疗晚期胃癌合并腹水的临床疗效观察[J].消化肿瘤杂志(电子版),2013,5(1):26-32. 被引量:11
-
5唐鸿生,崔书中,唐云强.腹腔热灌注化疗及其在胃肠道恶性肿瘤治疗中的应用[J].消化肿瘤杂志(电子版),2012,4(4):270-272. 被引量:8
-
6李雁,周云峰,梁寒,王华庆,郝继辉,朱正纲,万德森,钦伦秀,崔书中,季加孚,徐惠绵,魏少忠,许洪斌,锁涛,杨树军,谢丛华,杨肖军,杨国樑.细胞减灭术加腹腔热灌注化疗治疗腹膜表面肿瘤的专家共识[J].中国肿瘤临床,2015,42(4):198-206. 被引量:106
-
7梅列军,杨肖军,李雁,杨国梁.兔VX2腹膜转移癌模型的建立及转移特征[J].中华实验外科杂志,2009,26(7):857-857. 被引量:2
-
8李允山,房献平.甲状腺微癌一例[J].湖南医学,1996,13(5):320-320.
-
9梁青春,张新民.甲状腺乳头状癌VEGF—C表达、TAMs浸润与淋巴管生成的关系及临床意义[J].疑难病杂志,2009,8(10):599-601.
-
10郭旭峰,茅腾,吉春宇,谷志涛,陈文虎,方文涛.病理N1期胸段食管鳞癌根治术后复发转移危险因素分析[J].中华胃肠外科杂志,2013,16(9):831-834. 被引量:6