煤工尘肺合并睡眠呼吸暂停40例分析

Analysis of 40 patients with coal worker＇s pneumoconiosis combined with sleep apnea

目的 综合分析煤工尘肺合并睡眠呼吸暂停的临床特征并评价其意义.方法 对2006年2月至2009年12月我院40例住院煤工尘肺合并睡眠呼吸暂停患者进行多导睡眠监测,并对血常规、尿常规、血压、生化指标等进行检测.结果 煤工尘肺合并睡眠呼吸暂停主要表现为重叠低氧血症以及多器官功能损害,如高血压和心、肺、肾功能损害,红细胞增多,血糖、血脂、血尿酸升高等,并形成恶性循环加重上述损害.结论 煤工尘肺合并睡眠呼吸暂停可引起严重的低氧血症及高碳酸血症,并造成多器官系统损害,临床应充分认识,早期、合理和有效的治疗可逆转或延迟多器官功能的进一步损害,明显改善预后.

Objective We studied the clinical features and its significance of coal worker＇s pneumoconiosis combined with sleep apnea Methods In 40 patients with coal worker＇s pneumoconiosis combined with sleep apnea hospitalized from February 2006 to December 2009, polysomnography （ PSG） , blood routine, urine routine, blood pressure and biochemical indicators were measured and analyzed. Results Patients with coal worker＇ s pneumoconiosis combined with sleep apnea manifested mainly as duplicate hypoxemia and multi-organ dysfunction： high blood pressure, dysfunction of heart, lung and kidney, increase of serum glucose, blood lipids, blood uric acid and finally led a vicious cycle to aggravate the above mentioned damage. Conclusions In clinical, multiple-organ dysfunction resulted from severe hypoxemia and hypercapnia caused by coal worker＇s pneumoconiosis combined with sleep apnea, should be fully aware and give ational and effective treatment early to reverse or delay the further function damages of multiple organs, and therefore significantly improve the prognosis.