摘要
1型糖尿病是一种以胰岛B细胞受损为特征的自身免疫性疾病,目前尚无根治方法。近年来,用干细胞治疗1型糖尿病成为新的研究热点,为该病的治疗提供了新思路。本文就1型糖尿病的干细胞治疗研究进展作一综述。
出处
《癌变.畸变.突变》
CAS
CSCD
2010年第4期323-325,共3页
Carcinogenesis,Teratogenesis & Mutagenesis
参考文献28
-
1Best M,Carroll M,Hanley N,et al.Embryonic stem cells to beta-cells by understanding pancreas development[J].Mol Cell Endocrinol,2008,288(1/2):86-94.
-
2Gerecht NS,Itskovitz EJ.Cell therapy using human embryonic stem cells[J].Transpl Immunol,2004,12(3/4):203-209.
-
3Mitjavila GMT,Simonin C,Peschanski M.Embryonic stem cells:meeting the needs for cell therapy[J].Adv Drug Deliv Rev,2005,57 (13):1935-1943.
-
4Lumelsky N,Blondel O,Laeng P,et al.Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets[J].Scionce,2001,292(5520):1389-1394.
-
5Saldeen J,Kriz V,Agren N,et al.SHB and angiogenic factors promote KS cell differentiation to insulin-producing cells[J].Biochem Biophys Res Commun,2006,344(2):517-524.
-
6Ibii T,Shimada H,Miura S,et al.Possibility of insulin-producing cells derived from mouse embryonic stem cell for diabetes treatment[J].J Biosci Bioeng,2007,103(2):140-146.
-
7Cho YM,Lim JM,Yoo DH,et al.Betacellulin and nicotinamide sustain PDX1 expression and induce pancreatic beta-cell differentiation in human embryonic stem cells[J].Biochem Biophys Res Commun,2008,366(1):129-134.
-
8Vaca P,Berna G,Araujo R,et al.Nicotinamide induces differentiation of embryonic stem cells into insulin-secreting cells[J].Exp Cell Res,2008,314(5):969-974.
-
9Chen C,Zhang Y,Sheng X,et al.Differentiation d embryonic stem cells towards pancreatic progenitor cells and their transplantation into streptozotocin-induced diabetic mice[J].Cell Bid Int,2008,32(4):456-461.
-
10Stoffel M,Vallier L,Pedersen RA.Navigating the pathway from embryonic stem cells to beta cells[J].Semin Cell Dev Biol,2004,15 (3):327-336.
二级参考文献58
-
1周婷,孙侃.STZ诱导糖尿病大鼠模型制备及经验[J].农垦医学,2002,24(5):323-324. 被引量:8
-
2余卫,张洹,何冬梅.体外诱导小鼠胎肝间充质干细胞向胰岛B样细胞分化的研究[J].第二军医大学学报,2004,25(8):827-830. 被引量:12
-
3Li-BoChen Xiao-BingJiang LianYang.Differentiation of rat marrow mesenchymal stem cells into pancreatic islet beta-cells[J].World Journal of Gastroenterology,2004,10(20):3016-3020. 被引量:94
-
4喻永涛,惠国桢,陈镭,陆华,苗宗宁.人脐血间充质干细胞的分离培养与向神经元样细胞诱导分化的实验研究[J].苏州大学学报(医学版),2004,24(6):787-790. 被引量:14
-
5唐晓琼,赵智刚,王红祥,李秋柏,邹萍.人脐静脉来源间充质干细胞向神经样细胞分化的体外分离扩增实验[J].中国临床康复,2005,9(42):1-3. 被引量:2
-
6刘雅娟,李秀东,陈强,凌翎,刘丽珠,范洪学.骨髓间充质干细胞体外诱导分化为胰岛样细胞及其对坏死胰腺组织的修复[J].吉林大学学报(医学版),2005,31(6):836-838. 被引量:10
-
7张雷,秦新裕.小鼠异种胰岛移植排斥反应研究[J].中华实验外科杂志,2006,23(1):43-44. 被引量:8
-
8李贵士.胰腺干细胞移植治疗糖尿病[J].中国临床康复,2006,10(13):165-166. 被引量:5
-
9Fu YS Cheng YC Lin MY Cheng H Chu PM Chou SC Shih YH Ko MH Sung MS.Conversion of human umbilical cord mesenchymal stem cells in Wharton's jelly to dopaminergic neurons in vitro: potential therapeutic application for Parkinsonism[J].中国生物学文摘,2006,20(10):22-23. 被引量:140
-
10Robertson RP. Islet transplantation as a treatment for diabetes - a work in progress, N Engl J Med 2004;350(7):694-705
共引文献61
-
1杨显富,钟明,邓绍平.糖尿病细胞治疗供体来源的现状[J].实用器官移植电子杂志,2013,1(5):311-314. 被引量:5
-
2李莉蓉,朱大龙.1型糖尿病治疗研究进展[J].中华糖尿病杂志,2010,2(1). 被引量:5
-
3中华医学会糖尿病学分会.中华医学会糖尿病学分会关于干细胞移植治疗糖尿病的立场声明[J].中华糖尿病杂志,2010,2(6). 被引量:36
-
4朱大龙,陈丽,李莉蓉.干细胞移植治疗糖尿病的临床研究进展[J].中华糖尿病杂志,2010,2(6). 被引量:1
-
5赵海莲.人端粒酶反转录酶转染的骨髓间充质干细胞移植治疗大鼠糖尿病[J].中国组织工程研究,2015,19(6):903-907. 被引量:1
-
6袁路,陈维平.胰腺干细胞体外扩增培养体系的建立[J].实用儿科临床杂志,2007,22(13):1025-1027.
-
7叶海青,范东燕,刘雅娟,陈强,范洪学.胰腺源间充质干细胞对大鼠胰腺损伤的修复作用[J].吉林大学学报(医学版),2008,34(4):551-555. 被引量:2
-
8孙艳,张洹.小鼠胎肝间充质干细胞的分离及鉴定[J].基础医学与临床,2008,28(12):1303-1307.
-
9孙晓晖,王颜刚.干细胞移植定向分化为胰岛β细胞治疗糖尿病[J].中国组织工程研究与临床康复,2009,13(1):165-168. 被引量:12
-
10效梅,安立龙,杨学义,窦忠英.移植源于人单克隆胰腺干细胞的胰岛治疗大鼠糖尿病[J].中国兽医学报,2009,29(2):191-195. 被引量:4
同被引文献43
-
1刘道永,孙冰生,武金才,李国才,任宁,高冬梅,钦伦秀.应用滤过富集法检测肝癌患者外周血中肿瘤细胞[J].中华实验外科杂志,2007,24(4):498-499. 被引量:6
-
2Giralt S A, Horowitz M, Weisdorf D, et al. Review of stem-cell transplantation for myelodysplastic syndrmoes in older patients in the context of the Decision Memo for Allo- geneic Hematopoietic Stem Cell Transplantation for Myelo- dysplastic Syndrome emanating from the Centers for Medi- care and Medicaid Services [ J ]. J Clin Oncol, 2011,29 (5) :566-572.
-
3Brignier A C, Gewirtz A M. Embryonic and adult stem celltherapy [ J ]. J Allergy Clin Immunol, 2010,125 (2) :336-344.
-
4Sharp J, Frame J, Siegenthaler M, et al. Human embryon- ic stem cell-derived oligodendrocyte progenitor eell trans- plants improve recovery after cervical spinal ord injury[ J ]. Stem Ceils, 2010,28 ( 1 ) : 152-163.
-
5Kisseleva T, Gigante E, Brenner D A. Reeent advances in liver stem cell therapy J]. Curr Opin Gastroenterol, 2010, 26(4) :395-402.
-
6Gekas C, Graf T. Induced pluripotent stem cell-derived human platelets: one step closer to the clinic [ J]. J Exp Med, 2010,207(13) :2781-2784.
-
7Wilmur I, Sehnieke A E, McWhir J, et al. Viable off- spring derived from fetal and adult mammalian ceils [ J]. Nature, 1997,385(6619) :810-813.
-
8Wakayama T, Perry A C, Zuceotti M. Full-term develop- ment of mice from enucleated oocytes injected with cumu- lus cell nuclei [ J ]. Nature, 1998,394 ( 6691 ) :369-374.
-
9Briggs R, King T J. The transplantation of living nuclei from blastula cells into enucleated frog eggs[ J]. Proc Natl Acad Sci USA, 1952,38(5) :455-463.
-
10Wilmut I, Schnieke A E, McWhir J, et al. Viable off- spring derived from fetal and adult mammalian cells [ J ]. Nature, 1997,385(6619) :810-813.
-
1干细胞治疗糖尿病的研究进展及临床转化[J].中华医学信息导报,2016,0(3):8-8.
-
2韩丹.“年轻”肠病,偏爱年轻人[J].中国家庭医生,2014,0(17):8-9.
-
3王黛菲.预防痛风复发 多饮水多吃蔬菜[J].健康博览,2008(7):27-27.
-
4王秀艳.糖尿病的自我护理及健康教育[J].医学信息(下旬刊),2010(2):248-248.
-
5李正方,曲英.骨质疏松患者的健康教育[J].疾病监测与控制,2008,2(7):436-438.
-
6天下资讯[J].大众健康,2014,0(8):12-12.
-
7说“高科技降糖”,你要当心[J].养生保健指南(中老年健康),2016,0(4):13-14.
-
8刘红囡.百汇爱心 跨越国界——新加坡医疗保健服务及百汇康护集团扫描[J].中国经贸,2004,0(9):82-83.
-
9纪颖婕.骨质疏松症,你知道多少[J].保健医苑,2005(10):10-12. 被引量:1
-
10周一海.选择适合你的足部保健方法[J].家庭健康(医学科普),2015,0(4):18-18.