黄芪、β-七叶皂苷钠注射液配合应用治疗肾病综合症Ⅰ型30例

Investigation on Clinical Curative Effect of Radix Astragali seu Hedysari and Sodium β aescin Injection Combination for Nephortic Syndrome Type Ⅰ on 30 Cases

为寻求治疗肾病综合症Ⅰ型安全有效的药物，对５２例肾病综合症Ⅰ型患者随机分为治疗组与对照组。其中治疗组３０例应用黄芪注射液及β七叶皂苷钠注射液配合静脉滴注，对照组２２例单纯用西药治疗，４周后进行两组疗效评估。结果，治疗组总有效率９０％，优于对照组６８．２％（Ｐ＜０．０５）；两组患者尿蛋白均减少，血浆白蛋白均增高，但治疗组优于对照组（Ｐ＜０．０１～０．００１），胆固醇、纤维蛋白原减少。

To seek the safe and effective drug for nephrotic syndrome type Ⅰ.52 patients suffering from nephrotic syndrome type Ⅰ were grouped into the therapy group (30 cases) and control group (22 cases) at random.The therapy group was intravenously dripped with Radix Astragali seu Hedysari and Sodium β aescin Injection combination.The control group was treated with chemical drug alone.The curative effects of two groups were compared after 4 weeks.As a result,the total effective rate of therapy group (90%) is higher than that of control group (68.2%) ( P< 0.05).The urinary protein levels of patients in both groups decrease.Their plasma albumin levels increase.But the therapy group is superior to the control group ( P< 0.01～0.001).Also the therapy group is prior to the control group in decreasing of cholesterol and fibrinogen.