摘要
目的探讨小儿病毒性脑炎与EB病毒感染的关系。方法利用巢式PCR法对确诊病毒性脑炎64例(设为观察组)小儿血清、脑脊液进行EB病毒DNA检测,并在同期住院确诊为支气管肺炎26例(设为对照组)小儿血清进行EB病毒DNA检测。结果观察组与对照组患者血清EB病毒DNA检测阳性率分别为3.13%、3.85%,统计学上无差异;观察组患者脑脊液EB病毒DNA检测均为阴性。结论本地区小儿一定程度受EB病毒感染,但不是引起散发的病毒性脑炎主要病原体。
Objective To explore the relationship between viral encephalitis infant and EB infection. Method 64 infants with viral encephalitis （observation group） and 26 with bronchopneumonia （control group） were included in this study. reverse transcription-nested PCR（RT-nPCR）was used to detect the DNA of EB virus in the serum and ncurolymph respectively. Results Detection rate of serum DNA virus in the observation group and the control group was 3.13%, 3.85% respectively, and no statistical signifi cance was observed, meanwhile, DNA detection of ncurolymph EB virus were negative in both groups. Conclusion EB virus could attack infants in the area to some extent, but it is not the major pathogen to cause sporadic viral encephalitis.
出处
《中国医药指南》
2010年第23期9-10,共2页
Guide of China Medicine
关键词
儿童
病毒性脑炎
脑脊液
EB病毒
DNA
Children
Viral encephalitis
Cerebrospinal fluid
EB virus
DNA
