布地奈德吸入对婴幼儿喘息性疾病喘息复发的影响

Preventive Effects of Budesonide Atomizeing Inhalation on Relapses of Wheezing and Coughing in Children Recovered from Asthmatoid Diseases

目的探讨婴幼儿喘息性疾病后喘息发作的预防方法。方法收集儿科住院的0～2岁的喘息性疾病患儿186例,均予常规综合治疗。对其中87例加用布地奈德悬液雾化吸入,时间为7～12d;其余99例患儿为对照组。观察1年内2组患儿喘息、咳嗽发作情况。结果治疗组患儿在1年内的喘息、咳嗽发生例数较对照组明显减少,差异有统计学意义。结论短疗程吸入布地奈德悬液可减少婴幼儿喘息性疾病后喘息、咳嗽的发作,对降低哮喘发病率有积极的临床意义。

Objective To investigate the preventive therapy of wheezing episode in infants recovered from asthmatoid diseases.Methods One hundred and eighty six cases of hospitalized infants with asthmatoid diseases aged 0 to 2 years were randomly divided into experiment group（87 cases）and control group（99 cases）.Based on the routine combined therapy,the experiment group was given an additional atomizeing inhalation of Budesonide suspension for 7-12 days.The information on relapses of wheezing and coughing in both groups were collected by follow-up visits within 1 year.Results The relapses rate of wheezing（P〈0.05）and coughing（P〈0.01）were obviously decreased in the experiment group.Conclusion Short course inhalation of Budesonide suspension is beneficial in decreasing the relapses of wheezing and coughing in infants recovered from asthmatoid diseases,as well as diminishing rate of child asthma.