期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

碳青霉烯类抗菌药物耐药的大肠埃希菌KPC酶检测与分析 被引量：1

原文传递
导出
摘要 大肠埃希菌是医院内感染和社区获得性感染的重要病原菌,其耐药性十分严重.我们在我院分离的一株碳青霉烯类抗菌药物耐药的大肠埃希菌E902774的耐药机制研究中存在A类碳青霉烯酶KPC（肺炎克雷伯菌碳青霉烯酶）-2酶.
作者 姚慧琳 陆士海 刘培明
机构地区 安徽淮北矿业集团总医院检验科
出处 《中华微生物学和免疫学杂志》 CAS CSCD 北大核心 2010年第7期685-686,共2页 Chinese Journal of Microbiology and Immunology
关键词 抗菌药物耐药 大肠埃希菌 碳青霉烯类 酶检测 社区获得性感染 碳青霉烯酶 肺炎克雷伯菌 医院内感染
分类号 R446.5 [医药卫生—诊断学]
  • 相关文献

参考文献3

  • 1沈继录,朱德妹,吴卫红,徐晓刚,王明贵.革兰阴性杆菌碳青霉烯酶产生与细菌耐药性关系的研究[J].中华检验医学杂志,2008,31(4):408-414. 被引量：66
  • 2Bonomo RA,Szabo D.Mechanisms of multidrug resistance in Acinetobacter species and Pseudomonas aeruginosa.Clin Infect Dis,2006,43 Suppl 2:S49-56.
  • 3Cai JC,Zhou HW,Zhang R,et al.Emergence of Serratia marcescens,Klebsiella pneumoniae,and Escherichia coli isolates possessing the plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in intensive care units of a Chinese hospital.Antimicrob Agents Chemother,2008,52(6):2014-2018.

二级参考文献12

  • 1骆俊,沈继录,徐晓刚,胡付品,朱德妹,汪复.耐碳青霉烯类抗生素不动杆菌的β内酰胺酶研究[J].中国感染与化疗杂志,2007,7(2):79-83. 被引量：15
  • 2Clinical and Laboratory Standards Institute M100-S15. Performance standards for antimicrobial susceptibility testing. 15th Informational Supplement, 2005.
  • 3J.萨姆布鲁克,DW.拉塞尔,著.分子克隆实验指南.黄培堂,等译.3版.北京:科学出版社,2002.
  • 4Tenover FC, Arbeit RD, Goering RV, et al. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol, 1995,33 : 2233-2239.
  • 5Bonomo RA, Szabo D. Mechanisms of mulfidrug resistance in acinetobacter species and Pseudomonas aeruginosa. Clin Infect Dis,2006, 43 (Suppl 2): S49-S56.
  • 6Walsh TR, Toleman MA, Poirel L, et al. Metallo-β-1actamases: the quiet before the storm? Clin Microbiol Rev,2005, 18: 306- 325.
  • 7Poirel L, Nordmann P. Carbapenem resistance in Acinetobacter baumannii: mechanisms and epidemiology. Clin Microbiol Infect, 2006,12: 826-836.
  • 8Wei ZQ, Du XX, Yu Ys, et al. Plasmid-mediated KPC-2 in a Klebsiella pneumoniae isolate from China. Antimicrob Agents Chemother, 2007,51: 763-765.
  • 9胡付品,叶信予,吴培澄,吴湜,朱德妹,汪复.2005年上海华山医院细菌耐药性监测[J].中国感染与化疗杂志,2007,7(4):233-237. 被引量：58
  • 10倪语星.2005年中国CHINET铜绿假单胞菌耐药性分析[J].中国感染与化疗杂志,2007,7(4):274-278. 被引量：49

共引文献65

同被引文献34

  • 1Nordmann P, Cuzon G,Naas T. The real threat of KlebsieUa pneu- moniae carbapenemase-producing bacteria [ J ]. Lancet Infect Dis, 2009,9(4) :228-236.
  • 2Nordmann P, Naas T, Poirel L. Global spread of Carbapenemase- producing Enterobacteriaceae [ J ]. Emerg Infect Dis, 2011, 17 (10) : 1791-1798.
  • 3Navon-Venezia S, Chinelnitsky I, Leavitt A, et al. Plasmid-mediated imipenem-hydrolyzing enzyme KPC-2 among multiple carbapenem- resistant Escherichia coli clones in Israel [ J ]. Antimicrob Agents Chemother,2006,50(9) :3098-3101.
  • 4Bratu S, Brooks S,Burney S, et al. Detection and spread of Esche- richia coli possessing the plasmid-borne carbapenemase KPC-2 in Brooklyn, New York [ J ]. Clin Infect Dis,2007,44 (7) :972-975.
  • 5Landman D, Urban C, Backer M, et al. Susceptibility profiles, mo- lecular epidemiology, and detection of KPC-produeing Escherichia coli isolates from the New York City vicinity[ J]. J Clin Mierobiol, 2010,48 ( 12 ) :4604 -4607.
  • 6Urban C, Bradford PA, Tuekman M, et al. Carbapenem-resistant Escherichia coli harboring Klebsiella pneumoniae earbapenemase beta-lactamases associated with long-term care facilities [ J ].Clin Infect Dis,2008,46( 11 ) :e127-e130.
  • 7Petrella S, Ziental-Gelus N, Mayer C, et al. Genetic and structural insights into the dissemination potential of the extremely broad- spectrum class A beta-laetamase KPC-2 identified in an Escherichia coli strain and an Enterobacter cloacae strain isolated from the same patient in France [ J ]. Antimicrob Agents Chemother, 2008, 52(10) :3725-3736.
  • 8D'Alineourt Carvalho-Assef AP,Leao RS,da Silva RV ,et al. Esch- erichia coli producing KPC-2 carbapenemase:first report in Brazil [J]. Diagn Mierobiol Infect Dis,2010,68(3) :337-338.
  • 9Zhang R, Zhou HW, Cai JC, et al. Plasmid-mediated carbapenem- hydrolysing beta-lactamase KPC-2 in earbapenem-resistant Serratia marcescem isolates from Hangzhou, China [ J ]. J Antimicrob Che- mother,2007,59 ( 3 ) :574-576.
  • 10Zhang R, Yang L, Cai JC, et al. High-level carbapenem resistance in a Citrobacterfreundii clinical isolate is due to a combination of KPC-2 production and decreased porin expression [ J ]. J Med Mi- crobio1,2008,57 ( Pt 3 ) :332-337.

引证文献1

二级引证文献10

中华微生物学和免疫学杂志
2010年 第7期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部