接种重组乙型肝炎疫苗低无应答的研究进展

Advances in the research of low- and non.responsiveness after immunization with recombinant hepatitis B vaccine

接种乙型肝炎（乙肝）疫苗是人群预防乙肝的关键措施,但接种乙肝疫苗后,约5%～10%免疫人群呈现抗体低无应答.此文对接种重组乙肝疫苗低无应答的研究进展作一综述.

The key strategy to prevent hepatitis B is immunization with hepatitis B vaccine,but after immunization.about 5%-10% of the vaccinees are low-and non-responders to hepatitis B vaccine.This review summarizes the research progress in low-and non-responsiveness after recombinant hepatitis B vaccination.