阻塞性睡眠呼吸暂停低通气综合征与胰岛素抵抗关系的研究进展

Advances in researching relationship between obstructive sleep apnea-hypopnea syndrome and insulin resistance

有研究表明,中心性肥胖是阻塞性睡眠呼吸暂停低通气综合征（OSAHS）的主要危险因素,可导致胰岛素抵抗.OSAHS患者存在胰岛素抵抗,中心性肥胖可能是联系OSAHS和胰岛素抵抗的中间环节.早期开展经鼻持续气道正压通气治疗OSAHS,可提高组织对胰岛素的敏感性,促进组织对葡萄糖摄取利用,从而减轻或避免产生胰岛素抵抗.

The studys have provided evidence that abdominal obesity is important factor in obstructive sleep aphea-hypopnea syndrome may lead to insulin resistance. Severe insulin resistance exists in obstructive sleep apnea-hypopnea syndrome. Abdominal obesity may be the central factor in the relationship between obstructive sleep apnea-hypopnea syndrome and insulin resistance. Treatment with continuous positive airway pressure may improve the sensitvity of insulin, increase the usage of glucose, decrease the insulin resistance.