丹红注射液治疗冠心病心绞痛的疗效观察

The Efficacy of the Treatment of Danhong Injection to Alumna Pectoris

目的:观察丹红注射液治疗冠心病心绞痛的临床疗效。方法:冠心病心绞痛患者128例,按1:1的比例,随机分为两组。对照组常规给予硝酸酯类、β受体阻滞剂、钙通道阻滞剂、阿司匹林等药物治疗;观察组在常规治疗的基础上,给予丹红注射液40ml加入5%葡萄糖250ml静脉滴注(有糖尿病者改用生理盐水),1次/d,连续2周;分别记录治疗前后心绞痛症状、心电图的变化及不良反应发生情况。结果:观察组心绞痛疗效总有效率93.8%,心电图疗效总有效率81.3%;对照组心绞痛疗效总有效率71.9%,心电图疗效总有效率59.4%,两者比较观察组均优于对照组(均P<0.01);两组治疗前后血、尿常规,出凝血时间及肝肾功能均无明显改变,未发现严重不良反应。结论:丹红注射液治疗冠心病心绞痛疗效显著,安全可靠,值得临床推广应用。

Objective：To observe the clinical effect of the treatment of Danhong injection to Pectoris. Method：To divide 128 cases of patients with angnia pectoris into two groups randomly by the ratio of ltol.To treat the control group with the drugs of Nitrates, β-blocker, Calcium charmel blockers and Aspirin,and so on;give the observer group 40ml Dnhong injection with 250ml of 5% Glucose infusion （Diabetes replaced with saline）, once a day for two weeks;angina symptoms, electrocardiographic changes and the incidence of adverse reactions should be recorded before and after the treatment. Result：the total effective of the angina and the dectrocardiographic in the observe group is 93.8% and 81.3%,while the control group ＇s 71.9% and 59.4%.the observer group is superior to the control group; there are no significant changes or no serious adverse reactions in blood, urine routine, the clotting time, liver and kidney function before and after the treatment. Conclusion： The effect of the treatment of Danhong injection to Pectoris is significant, safe and reliableand,and it should be promoted in clinical.