复方丹参注射液治疗糖尿病肾病的临床观察

Danshen Injection on Diabetic Nephropathy

目的探讨复方丹参注射液治疗非胰岛素依赖型糖尿病肾病的临床疗效。方法选取非胰岛素依赖型糖尿病肾病50例,随机分为治疗组及对照组。治疗组使用血管紧张素转换酶抑制剂(ACEI)药物+复方丹参注射液治疗,对照组单用血管紧张素转换酶抑制剂(ACEI)药物治疗。结果治疗组血肌酐、尿素氮及24h尿蛋白总量在治疗前的基础上均用不同程度降低,对照组血肌酐、尿素氮及24h尿蛋白总量在治疗前的基础上均用不同程度升高。结论中西结合治疗非胰岛素依赖型糖尿病肾病具有减少尿蛋白排泄,改善肾功能,延缓非胰岛素依赖型糖尿病肾病进程的疗效。

Objective To investigate the effect of Salvia injection in treating non-insulin-dependent diabetes mellitus nephropathy.Methods Non-insulin-dependent diabetes mellitus nephropathy,50 cases were randomly divided into treatment group and control group.Treatment group using angiotensin converting enzyme inhibitor（ACEI） drugs ＋ Danshen injection,the control group using angiotensin converting enzyme inhibitor（ACEI） therapy.Results The treatment group serum creatinine,urea nitrogen,and total 24-hour urine protein treatment on the basis of the different levels are lower in the control group serum creatinine,urea nitrogen,and total 24-hour urine protein on the basis of the treatment were used increased to varying degrees.Conclusion Integrated Chinese and Western treatment of non-insulin-dependent diabetic nephropathy with reduced urinary protein excretion and improve renal function,and delay of non-insulin-dependent diabetic efficacy of the process.