128例重症肌无力患者的胸腺病理分析

Pathologic features of 128 cases myasthenia gravis

目的:研究重症肌无力患者的胸腺病理改变及临床意义。方法:回顾性分析2008年8月至2009年8月,我院重症肌无力中心128例手术切除的胸腺病理表现。结果:128例患者中,胸腺增生77例(60.16%),胸腺瘤30例(24.22%),胸腺萎缩16例(12.42%),此外还有胸腺囊肿2例、转移癌1例、生殖细胞癌1例、鳞状细胞癌1例。胸腺瘤中AB型14例(10.94%),B2型8例(6.24%),B3型及B1型均3例(2.34%),A型2例(1.59%)。结论:根据不同的病理诊断指导临床术后治疗及预后分析。

Objective： To investigate the pathological features of thymus for myasthenia gravis,as well as the significance of clinical staging. Methods： Pathologic change of 128 cases with myasthenia gravis after thymectony was analyzed. Results： Among 128 cases of thymectony, 77（60.16%） cases had thymic hyperplasia, 31（24.22%） cases thymoma ,16（12.42%） cases of atrophy thymus gland 2 cases thymic cyst,1 case metastatis carcinoma,1 case germinoma,1 case spuamous cell carcinoma .Among the 31 cases of thymoma ,there were 14 （10.94%）cases of type AB thymoma,8 （6.24%）casesof type B2 thymoma, 3 （2.34%） cases of type B3 thymoma,3（2.34%） cases of B1 thymoma,2（1.59%） cases of type A.Conclusion： The pathological feature determination have an important clinical value for diagnosis ,prognosis evaluation and proper treatment of thyroid carcinoma.