摘要
目的 :研究石菖蒲醇提取物的抗惊厥作用。方法 :采用最大电休克发作 (MES)法 ,士的宁惊厥法和戊四氮最小阈发作 (MET)法 ,观察石菖蒲醇提取物对动物惊厥的影响。结果 :石菖蒲醇提取物能明显对抗大鼠、小鼠的最大电休克发作和小鼠的戊四氮最小阈发作及小鼠的士的宁的惊厥反应。结论 :石菖蒲醇提取物具有明显的抗惊厥作用。
OBJECTIVE:To observe the anticonvulsant action of ethanol extract of acorous gramineus soland(EEAGS).METHODS:The anticonvulsant action of EEAGS was investigated in Maximal Electroshock Seizure(MES),Strychine-induced convulsion and Metrazol threshold Seizure(MET),respectively.RESULTS:EEAGS(6,3g/kg) had an obvious effect against MES in both mice and rats and MET in mice,had an antagonism to strychinine-induced convulsion also.CONCLUSION:EEAGS had an obvious anticonvulsant effect.
出处
《中国现代应用药学》
CAS
CSCD
1999年第2期19-21,共3页
Chinese Journal of Modern Applied Pharmacy
关键词
石菖蒲醇提取物
抗惊厥作用
实验研究
extract of acorus gramineus soland,maximal electroshock seizure,strychinine-induced convulsion,metrazol minimal threshold seizure
