蒙古种沙土鼠背海马胆碱能神经局部分布

LOCAL CHOLINERGIC INNERVATION IN DORSAL HIPPOCAMPUS OF MONGOLIAN GIRBIL

目的 :对蒙古种沙土鼠背海马乙酰胆碱酯酶阳性纤维和末梢的局部分布作分区分层的研究。方法 :应用乙酰胆碱酯酶纤维染色法及计算机图像扫描和统计学分析等方法。结果 :背海马局部乙酰胆碱酯酶纤维和末梢的分布按密度从大到小排列为 :CA2、CA3区辐射层 >CA4区 (齿状回门区 ) >齿状回多形层 >齿状回下支分子层 >齿状回上支分子层、背海马分子层 >CA1、CA2、CA3区多形层。结论

Objective:To study the subcellular localization of AchE fibers and their terminals in the dorsal hippocampus of mongolian girbil. Methods: Stain technique of AchE containing axons and computer image analysis and data processing were used. Results: The density of these fibers and terminals in different regions, from the highest to the lowest, was in the following order: radial stratum of CA2, CA3 area>CA4 area (hilum of the dentate gyrus)>polymorphous stratum of dentate gyrus>molecular stratum of inferior dentate gyrus>molecular stratum of superior dentate gyrus, molecular stratum of dorsal hippocampus>polymorphous stratum of CA1～CA3 areas. Conclusion: The findings provide a morphological basis for the further study about the corresponding subcellular location of cholinergic projections to the dorsal hippocampus of mongolian girbil.