滇白珠化学成分的研究(Ⅲ)

Studies on the Chemical Constiuents of Yunnan Wintergreen Root (Gaultheria yunnanensis) (Ⅲ)

从滇白珠Ｇａｕｌｔｈｅｒｉａ ｙｕｎｎａｎｅｎｓｉｓ（Ｆｒａｎｃｈ．）Ｒｅｈｄ．根的石油醚部分分得 １０个化合物，其中８个化合物经理化性质和波谱分析，它们的结构分别鉴定为β－乙酰谷甾醇（Ⅰ），３β－乙酰基－１２，２５－二烯－达玛烷（Ⅱ），３β－乙酰氧基－２０（２９）－羽扇烯－２８－醛（Ⅲ），３β－乙酰齐墩果酸（Ⅳ），β－谷甾醇（Ⅴ），熊果酸（Ⅵ），豆甾醇（Ⅶ）和３β－羟基－２０（２９）－羽扇烯－２８－醛（Ⅷ）。其中Ⅱ为杜鹃花科植物中首次发现的达玛烷三萜类化合物，化合物Ⅰ、Ⅲ、Ⅷ为杜鹃花科植物中首次报道，其它４个化合物为从该植物中首次分得。

Ten compounds were isolated from the petroleum ether fraction of the root of Gaultheria yunnanensis (Franch.) Rehd.. The structures of eight of them were identified as 3β-acetylsitosterol (Ⅰ ), 3β acety1-12, 25-dien-dammarane (Ⅱ ), 3β--acetoxy-20 (29) -lupen-28-aldehyde (Ⅲ ), 3β-acetyloleanoic acid (Ⅳ ), β-sitosterol (Ⅴ ), ursolic acid (Ⅵ ), stigmasterol (Ⅶ ) and 3β-hydroxy-20 (29)-lupen-28-aldehyde (Ⅷ ) by chemical and spectral methods. Among these compounds, Ⅱ is a dammarane triterpenoid discovered for the first time in Ericaceae; Ⅰ,Ⅲ andⅧ have not been reported previously from Ericaceae; the other four compounds were obtained from the title plant for the first time.