甲硝唑联合双唑泰泡腾片治疗细菌性阴道病450例疗效观察

Clinical Observation on Metronidazole Combining with the Tablets of Metronidazole Clotrimazole and Clorhexidine Acetate Effervescent in Treating 450 Patients with Bacterial Vaginitis

目的观察口服甲硝唑联合阴道放置双唑泰泡腾片治疗细菌性阴道病临床疗效。方法选取900例细菌性阴道病患者,随机分两组,每组450例,治疗组:口服甲硝唑0.5g,每日3次,同时阴道放置双唑泰泡腾片每晚1片;对照组:口服甲硝唑片0.5g,每日3次;两组均用药7d为1个疗程,夫妇同治。结果治疗组一次性治愈率为98.22%,总有效率为100%,两组比较差异有统计学意义(P<0.05)。结论甲硝唑联合阴道放置双唑泰泡腾片治疗细菌性阴道病是一种高效、安全不良反应小、易被患者接受的治疗方法,值得临床上推广应用。

Objective To observe the clinical effect of metronidazole combining with the tablets of metronidazole clotrimazole and clorhexidine acetate effervescent inserted into vaginit in treating bacterial vaginitis.Methods 900 patients were divided into two groups randomly as treatment group and control group.Each group contained 450 patients.The treatment was treated with metronidazole 0.5 g,p.o tid,combining with the tablets of metronidazole clotrimazole and clorhexidine acetate effervescent inserted into vaginit,1 tablet qn;The control was only with metronidazole 0.5 g,p.o tid.Both were treated in a period for 7 days for coupls.Results In the treatment group the cure rate in 1 period of treatment was 98.22%,and the total effective rate was 100%,with significant differences between the two groups（P 0.05）.Conclusion Metronidazole p.o combining with the tablets of metronidazole clotrimazole and clorhexidine acetate effervescent inserted into vaginit in treating bacterial vaginitis is a therapy with high efficiency,safty,low toxic side effect and easy acceptability,and is worth to practice.