宫颈癌宫旁浸润150例相关因素分析

Related Factors of Parametrial Infiltration Among 150 Cases of Cervical Cancer

目的通过分析宫颈癌宫旁浸润与各临床病理因素的关系,探讨影响宫颈癌宫旁浸润的高危因素。方法收集乐山市人民医院行手术治疗的150例临床IA-IIB期宫颈癌患者的临床病理资料,将宫旁浸润与各临床病理因素之间的关系进行单因素χ2检验及多因素logistic回归分析。结果宫颈癌宫旁浸润率为16.7%(25/150)。单因素分析显示临床分期、间质浸润深度、肿瘤生长方式、肿瘤直径、淋巴结转移与宫旁浸润间具有相关性(P<0.05);多因素分析显示仅肿瘤生长方式、间质浸润深度、淋巴结转移与宫旁浸润相关。结论肿瘤生长方式、间质浸润深度、淋巴结转移为宫旁浸润的高危因素。

Objective To analyze the relationship between clinical-pathological parameters of cervical cancer and parametrial infiltration（ PI）, and explore the risk factors of PI. Methods The clinical pathological data of 150 patients with eervieal cancer at stage IA-IIB hospitalized in our hospital were collected. The correlation between clinical pathological parameters and PI was analyzed by univariable X^2 test and multivarlable logistic analysis. Results The parametrial infiltration rate （PIR） was 16.7% （25/150）. PI was correlated with the clinical stage, depth of stromal invasion, growth pattern of tumor, diameter of tumor, lymph-nodes metastasis indicated by univariable analysis （ P 〈 0. 05 ）, while by multivariable analysis, PI was correlated with the growth pattern of tumor, depth of stromal invasion and lymph-node metastasis. Conclusions Growth pattern of tumor, depth of stromal invasion and lymph-node metastasis were the high risk factors of PI.