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血清VEGF水平与冠状动脉病变程度的临床研究 被引量:3

The Correlation between Serum Level of Vascular Endothelial Growth Factor and Severity of Coronary Artery Stenosis.
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摘要 Objective To study the correlation between serum level of vascular endothelial growth factor(VEGF) and severity of coronary artery stenosis.Methods This study included 114 patients with coronary haert disease(CHD group) and 92 hearthy people(control group).The serum VEGF level was measured by ABC-ELISA in all cases and was compared with the severity of coronary artery stenosis.Results The level of VEGF in CHD group was significantly higher than that in control group(141.17±19.94pg/ml Vs 17.73±6.45pg/ml,P<0.01).The serum VEGF level in 2 or 3 coronary branches lesions subgroups was 129.52±19.87 pg/ml and 158.25±26.77pg/ml,respectively,which were significantly higher than that in single branch lesion subgroup(100.79±17.81pg/ml,P<0.01).Conclusions The serum VEGF level could reflect the severity of coronary artery stenosis. Objective To study the correlation between serum level of vascular endothelial growth factor(VEGF) and severity of coronary artery stenosis.Methods This study included 114 patients with coronary haert disease(CHD group) and 92 hearthy people(control group).The serum VEGF level was measured by ABC-ELISA in all cases and was compared with the severity of coronary artery stenosis.Results The level of VEGF in CHD group was significantly higher than that in control group(141.17±19.94pg/ml Vs 17.73±6.45pg/ml,P〈0.01).The serum VEGF level in 2 or 3 coronary branches lesions subgroups was 129.52±19.87 pg/ml and 158.25±26.77pg/ml,respectively,which were significantly higher than that in single branch lesion subgroup(100.79±17.81pg/ml,P〈0.01).Conclusions The serum VEGF level could reflect the severity of coronary artery stenosis.
出处 《心脑血管病防治》 2010年第4期257-258,共2页 CARDIO-CEREBROVASCULAR DISEASE PREVENTION AND TREATMENT
基金 云南省教育厅科研基金资助(04Y849C)
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参考文献3

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同被引文献41

  • 1陈美娟,屈晓冰,胡信群.冠心病患者血管内皮生长因子水平变化及其与冠状动脉病变程度的关系[J].中国老年学杂志,2005,25(9):1032-1033. 被引量:3
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