期刊文献+

钠通道阻断剂在三叉神经痛药物治疗中的应用 被引量:4

Sodium channel blocker in pharmacotherapy with trigeminal neuralgia
原文传递
导出
摘要 三叉神经痛(TN)是一种神经病性疼痛综合征,其主要临床表现是面部三叉神经分布区反复发作的阵发性剧痛,性质如针刺样、电击样或刀割样等,持续时间数秒到数分钟.多数患者在面部有"扳机点",可由轻触、温度变化、面部运动或空气流动等刺激诱发疼痛.
出处 《中华神经医学杂志》 CAS CSCD 北大核心 2010年第8期861-863,共3页 Chinese Journal of Neuromedicine
关键词 三叉神经痛 钠通道阻断剂 药物疗法 Trigeminal neuralgia Sodium channel blocker Pharmacotherapy
  • 相关文献

参考文献26

  • 1Sert H,Usta B,Muslu B.Successful treatment of a resistance trigrminal neuralgia patient by acupuncture[J].Clinica,2009,64(12):1225-1226.
  • 2Spina E,Perugi G.Antiepileptic drugs:indications other than epilepsy[J].Epileptic Disorders,2004,6(2):57-75.
  • 3Dib-Hajj SD,Yang Y,Waxman SG.Genetics and molecular pathophysiology of Nax 1.7-related pain syndromes[J].Adv Genet,2008,63:85-110.
  • 4Boucher T J,Okuse K,Bennett DL,et al.Potent analgesic effects of GDNF in neuropathic pain states[J].Science,2000,290(5489):124-127.
  • 5Jarvis MF,Honore P,Shieh CC,et al.A-803467,a potent and selective NaVl.8 sodium channel blocker,attenuates neuropathic and inflammatory pain in the rat[J].Proc Natl Acad Sci USA,2007,104(20):8520-8525.
  • 6Kort ME,Drizin I,Gregg RJ,et al.Discovery and biological evaluation of 5-aryl-2-furfuramides,potent and selective blockers of the NaV1.8 sodium channel with efficacy in models of neuropsthic and inflammatory pain[J].J Med Chem,2008 51(3):407-416.
  • 7Dib-Hajj SD,Black JA,Stephen G,et al.Votage-gated sodium channels:therapeutic targets for pain[J].Pain Me.d,2009,10(7):1260-1269.
  • 8长橹巧,薛一雪.通过作用于离子通道的药物来治疗疼痛——以钠通道阻断剂为中心[J].日本医学介绍,2001,22(9):388-390. 被引量:6
  • 9Brau ME,Dreimann M,Olschewski A,et al.Effect of drugs used for neuropathic pain management on tetrodotoxin-resistant Na+currents in rat sensory neurons[J].Anesthesiology,2001,94(1):137-144.
  • 10Liu J,Dai J,E L,et al.Trigeminal neuralgia may be caused by abnormality of the trigger zone[J].Med Hypotheses,2010,74(5):818-819.

共引文献5

同被引文献21

  • 1寿雯婷,张世红,陈忠.钠离子通道在神经病理性疼痛中的作用研究进展[J].浙江大学学报(医学版),2011,40(2):217-221. 被引量:11
  • 2于勇,孟箭,王旭光,张成彬.C臂引导下射频温控热凝术治疗原发性三叉神经痛临床应用[J].徐州医学院学报,2005,25(6):554-555. 被引量:6
  • 3O’Connor AB.Neuropathic pain:a review ofthe quality of life impact,costs,and cost-effect-iveness of therapy.Pharmacoeconomics,2009,27:95-104.
  • 4Marmura MJ.Intravenous lidocaine and mexiletinein the management of trigeminal autonomic ceph-alalgias.Curr Pain Headache Rep,2010,14:145-150.
  • 5Carroll IR,Kaplan KM,Mackey SC.Mexiletine th-erapy for chronic pain:suvival analysis identifiesfactors predicting clinical success.J Pain SymptomManage,2008,35:321-326.
  • 6Choi JS,Zhang L,Dib-Hajj SD,et al.Mexiletineres-ponsive erythromelalgia due to a new Na(v)1.7mutation showing rsedependent current fall-off.Exp Neurol,2009,216:383-389.
  • 7Haleem S, Siddiqui AK, Mowafi HA, et al. Brief reports : nerve stimulator evoked motor response predicting a successful supracla- vicular brachial plexus block [ J ]. Anesth Analg, 2010 , 110 (6) : 1745-1746. DOI: 10. 1213/ANE. 0b013e3181daS2ff.
  • 8Wang XH, Zhou C, Shen GJ, et al. Long-term outcomes of percu- taneous retrogasserian glycerol rhizotomy in 3370 patients with tfi- geminal neuralgia [ J ]. Turk Neurosurg , 2013,21 ( 1 ) : 48-52. DOI: 10. 5137/1019-5149. JTN. 3550-10.1.
  • 9安志明,王杰军.神经病理性疼痛的药物治疗进展[J].中国疼痛医学杂志,2008,14(1):42-44. 被引量:17
  • 10吴宝红,王永安,郑建全.电压门控性钠通道亚型和神经病理性疼痛[J].国际药学研究杂志,2009,36(3):189-193. 被引量:3

引证文献4

二级引证文献12

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部