抗慢性丙型病毒性肝炎药物研究进展

The Research Progression of Curing Chronic HCV Drugs

目的:综述慢性丙型病毒性肝炎临床有效、易耐受的新颖疗法。方法:论述重组IFNα和重组人白蛋白的基因融合蛋白、利巴韦林替代物、丝氨酸蛋白酶抑制剂、α糖苷酶抑制剂、HCV多聚酶抑制剂、丙型肝炎疫苗和中成药临床试验效果。结果:明确了抗HCV药物治疗的新方法。结论:随着人们对HCV病毒生命周期的深入认识,新治疗靶位不断增加,抗HCV药物有了较大的发展。

Objective：To Probe the New Therapeutic of Curing Chronic HCV.Methods：To Expound the Effect of clinical trial,Albuferon,Viramidine,Telaprevir and SCH,celgosivir,Valopicitabin（NM283） and R1479,the HCV vaccine,Songzhi Wan and Chuilan Qingdu Keli.Results：To definitize the new Method of Anti-HCV therapy.Conclusion：With the people the virus life cycle of HCV depth understanding of new therapeutic targets growing anti-HCV drugs has been considerable development.