原发性肝癌患者经皮肝动脉化疗栓塞术后生存质量与疲乏的相关性研究

Study on Quality of Life and Fatigue in Patients with Primary Liver Cancer after Transcatheter Arterial Chemoembolization

目的探讨原发性肝癌患者经皮肝动脉化疗栓塞术后生存质量与疲乏的相关性。方法采用便利抽样,选取113例经皮肝动脉化疗栓塞术后原发性肝癌患者,采用癌症治疗功能评价量表及Piper疲乏修正量表,调查其化疗栓塞术后4周左右的生存质量和疲乏情况,分析两者的相关性。结果本组对象术后的生存质量总分为(57.98±10.82)分,比国内其他恶性肿瘤患者低,其中情感状况得分最低;79.7%患者经历中度疲乏,情感疲乏最为严重;生存质量得分与疲乏得分呈负相关(r=-0.35,P<0.01)。结论缓解疲乏可能是提高肝癌患者经皮肝动脉化疗栓塞术后生存质量的重要措施。

Objective To explore the relativity between quality of life （QoL） and fatigue in patients with primary liver cancer after transcatheter arterial chemoembolization （TACE）. Methods Convenience sampling was applied in this study and 113 patients with primary liver cancer after TACE were recruited. QoL and Fatigue were measured by Functional Assessment of Cancer Therapy- General （FACT-G） and Pipe Fatigue Scale-R respectively. Results The score of QoL in patients with primary liver cancer after TACE was （57.98±10.82）, which was lower than patients with other cancers, emotional status dimension was the worst; 79.7% patient experienced moderate fatigue, and emotional fatigue was the worst; QoL was negatively related with fatigue （r=-0.35,P〈0.01）. Conclusion Relieving fatigue could be effective in improving QoL in patients with primary liver cancer after TACE.