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抗痛风新药——非布索坦 被引量:2

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出处 《中国药学杂志》 CAS CSCD 北大核心 2010年第15期1197-1198,共2页 Chinese Pharmaceutical Journal
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  • 1OKAMOTO K, EGER B T, NISHINO T, et al. An extremely potent inhibitor of xanthine oxidoreductase. Crystal structure of the enzyme-inhibitor complex and mechanism of inhibition[ J ]. J Biol Chem, 2003, 278 (3) : 1848-1855.
  • 2Full Prescribing Information of Uloric [ EB/OL]. http: //www. uloric, com.
  • 3MICHAEL A B H, RALPH S J R, ROBERT L, et al. Febuxostat, a novel nonpurine selective inhibitor of xanthine oxidase. A twenty- eight day, multicenter, phase II, randomized, double-blind, placebo-controlled, dose-response clinical trial examining safety and efficacy in patients with gout[ J]. Arthritis Rheum, 2005, 52(3) : 916-925.
  • 4BECKER M A, SCHUMACHER H R J R, WORTMANN R L, et al. Febuxostat compared with allopurinol in patients with hyperttricemia and gout[J]. N Engl J Med, 2005, 353(23) : 2450-2460.
  • 5RALPH H, SCHUMACHER J R, MICHAEL A, et al. Effects of febuxostat versus allopurinol and placebo in reducing serum urate in subjects with hyperuricemia and gout: a 28-week, phase III, randomized, double-blind, parallel-group trim [ J ]. Arthritis Rheum, 2008, 59( 11 ) : 1540-1548.

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