摘要
目的:了解本地区女性生殖道支原体感染及对抗菌药物的敏感状况,给临床用药提供参考依据。方法:回顾性分析2006年6月-2009年10月临床送检的660份女性泌尿生殖道分泌物标本支原体培养及药敏试验结果。结果:①支原体培养总阳性率为36.96%,其中解脲支原体(Uu)为31.82%,显著高于人型支原体(Mh)的1.68%和Uu+Mh混合感染的3.48%(P<0.01);②10种抗生素体外敏感率前三位的是多西霉素(DOX)、米诺环素(MIN)、克拉霉素(CLA),分别为96.72%、92.21%、88.52%,壮观霉素(SPE)耐药率最高为76.23%;③Uu合并Mh感染相比单纯Uu感染耐药率最高、耐药范围扩大,其中克拉霉素(CLA)、罗红霉素(ROX)、阿齐霉素(AZI)耐药率增高明显。结论:对于泌尿生殖道支原体感染,应重视支原体培养及药敏试验,根据药敏结果选择治疗药物,合理使用抗生素。
Objective:Understanding of the region in female reproductive tract infection of mycoplasma and antimicrobial sensitivity of the situation,provide some references to the clinical use of drugs.Methods:A retrospective analysis from June 2006 to October 2009 submission of the 660 clinical female urogenital specimens secretion mycoplasma culture and drug susceptibility test results.Results:① mycoplasma culture positive rate was 36.96%,of which ureaply urealyticum(Uu) to 31.82%,significantly higher than that of people with mycoplasma hominis(Mh) 1.68% and Uu+Mh mixed infection of 3.48%(P0.01);② 10 antibiotics in vitro is more sensitive to the rate of the top three West doxycycline(DOX),minocycline(MIN),clarithromycin(CLA),respectively,96.72%,92.21%,88.52%,spectinomycin(SPE) resistance rates of up to 76.23%;③ Uu merger Mh infection resistant than simple infection of the highest rates of Uu,resistance to extend,in which clarithromycin(CLA),roxithromycin(ROX),azithromycin(AZI) resistance rates increased significantly.Conclusion:Mycoplasma infection,mycoplasma should pay attention to culture and sensitivity test,according to susceptibility results of the choice of treatment drugs,rational use of antibiotics.
出处
《中国卫生检验杂志》
CAS
2010年第7期1718-1719,共2页
Chinese Journal of Health Laboratory Technology
关键词
生殖道
支原体感染
培养
药敏试验
Reproductive tract
Mycoplasma infection
Culture
Test of drug sensitivity