肃南裕固族中小学生乙肝表面抗原阳性率调查及影响因素分析

Hepatitis B surface antigen positive rate and risk factors analysis of primary and secondary students in Sunan province Yugu autonomous

目的:了解甘肃省张掖市肃南裕固族自治县裕固族中小学生乙肝表面抗原(HBsAg)携带情况及主要影响因素。方法:随机抽取943名中小学生,进行乙肝知识问卷调查,同时采取静脉血,用ELISA法检测HBsAg,并对HBsAg阳性者进行乙肝三系统和肝功能检验。结果:HBsAg阳性率9.12%,男性阳性率为10.26%,女性阳性率为7.62%,男、女HBsAg阳性率差异有统计学意义(χ2=8.12,P<0.01);HBsAg阳性率6～8岁年龄段最低,高峰在14～16岁年龄段。学生乙肝知识知晓率为34.46%,乙肝疫苗接种率为65.43%;50.67%的HBsAg阳性学生家庭中至少有1个以上HB-sAg携带者,母亲为HBsAg携带者占56.10%。结论:乙肝疫苗接种、母婴垂直传播、生活密切接触是影响裕固族中小学生HBsAg携带率的主要因素。

Objective：In order to understand hepatitis B surface antigen（HBsAg） carrying case and the main factors of Yugur students in Zhangye,Gansu province Yugu Autonomous.Methods： 943 randomly selected primary and secondary students were conducted a questionnaire survey of hepatitis B knowledge,while taking venous blood,using ELISA assay HBsAg,and HBsAg positive for hepatitis B three system and liver function tests.Results： HBsAg positive rate was 9.12%,the male positive rate was 10.26%,female-positive rate was 7.62%,male and female HBsAg positive rate was significantly（χ2 = 8.12,P0.01）;The minimum of HBsAg positive rate was in 6～8 year-old-age group,the peak was in the 14～16 year-old-age group.Hepatitis B knowledge among the students was 34.46%,hepatitis B vaccination rate was 65.43%.There was one or more carriers of HBsAg at least in the families of 50.67% of HBsAg-positive students.HBsAg carrier mothers accounted for 56.10%.Conclusion： The hepatitis B vaccination,maternal transmission,living close contacts is the main factors of Yugurs HBsAg carrier rate.