吉米沙星治疗泌尿系反复感染的临床疗效观察

Effect and Safety of Gemifloxacin in Treatment of Urinary Tract Infections

目的:探讨吉米沙星治疗泌尿系反复感染的临床疗效与安全性。方法:103例泌尿系反复感染患者随机分为两组,治疗组52例口服吉米沙星320 mg,qd,对照组51例口服左氧氟沙星200 mg,bid,疗程均为10～14 d。结果:两组患者临床总有效率分别为92.31%和86.27%,两组差异无统计学意义(P>0.05)。细菌清除率分别为86.0%和65.9%,两组比较有显著差异(P<0.05)。且未见严重不良反应。结论:吉米沙星治疗泌尿系反复感染安全、有效、使用方便,是治疗泌尿系反复感染的选择。

Objective ： To evaluate the therapeutic effect and safty of gemifloxacin in treatment of urinary tract infections. Method： One hundred and three patients with urinary tract infections were divided randomly into two groups, which 52 cases in therapy group re- ceived Gemifioxacin and 51 cases in control group received Levofloxacin for 14 days. Result： The effective rate of two groups was 92. 31% and 86. 27%, respectively. There was no significant differences between two groups （P 〉 0. 05 ）. The rate of eliminating the bacteria was 86.0% ,65.9% ,respectively. There was significant differences between two groups （P 〈 0. 05 ）. There was no severe adverse reactions in the two groups. Conclusion： Gemifloxacin is effective and safe in treatment of urinary tract infections, and it will be a new choiee for severe urinary tract infections.