医院金黄色葡萄球菌的耐药性分析

Analysis of Drug-resistance of Staphylococcus aureus

目的调查医院临床分离的金黄色葡萄球菌(SAU)的耐药性,为临床医师合理使用抗菌药物提供科学依据。方法对189株SAU的分布和耐药性进行调查分析,SAU培养与鉴定严格按照《全国临床检验操作规程》进行,药物敏感试验采用K-B法。结果医院耐甲氧西林金黄色葡萄球菌(MRSA)分离率为36.5%;MRSA对抗菌药物的耐药率均高于甲氧西林敏感金黄色葡萄球菌(MSSA)。结论加强细菌耐药性的监控工作,是预防医院感染的有效措施。

OBJECTIVE To investigate the drug-resistance of Staphylococcus aureus（SAU） isolated clinically in Renming hospital of Dawu county and provide scientific evidence for clinically reasonable application of antibiotics.METHODS The clinical distribution and drug-resistance of 189 SAU strains were investigated and analyzed.The cultivation and identification of SAU were performed according to National Clinical Laboratory Operating Procedure.K-B method was used for antimicrobial susceptibility testing.RESULTS Isolating rate of methicillin resistant staphylococcus aureus（MRSA） arrived at 36.5%.The drug-resistance rates of antibiotics in MRSA were all higher than those in methicillin sensitive staphylococcus aureus（MSSA）.CONCLUSIONS Strengthening monitor of drug-resistance is an effective measure to prevent nosocomial infections.