2,6-二烷氧基(羟基)苯乙酮的苄腙和甲腙合成吲唑类化合物

The Synthesis of Indozoles from Substituted Hydranones of 2.6-dialkoxyl (hydroxyl) Acetophenones

在多聚磷酸存在下，２，４６－二烷氧基苯乙酮的苄腙和甲腙可以发生环化反应，生成产率较高的吲唑类化合物。根据实验结果，我们推测反应的关键步骤为关核进攻，化合物的结构均经元素分析，ＩＲ，＾１Ｈ ＮＭＲ和ＭＳ确定。

In the presence of PPA ,2.6- dialkoxyl ( hydroxyl) acetophenone hydrazones were cyclized to give indazoles. According to the experimental results, it was assumed that the cyclization was taken by nucleophilic attack. All the new compound were identified by elemental and spectral analyses.