氨基酮戊酸光动力疗法治疗尖锐湿疣的临床观察

Clinical efficacy of ALA-PDT in the treatment of condyloma acuminatum

目的 观察应用氨基酮戊酸光动力疗法（ALA-PDT）治疗尖锐湿疣的疗效.方法 应用ALA-PDT治疗尖锐湿疣36例.结果 经治疗后疗效评价,治愈33例（91.67%）,好转35例（97.22%）,复发3例（8.33%）.2例发生不良反应,发生率为5.56%.结论 ALA-PDT治疗尖锐湿疣具有相对简单、有效、安全、复发率低的特点,特别是对于特殊部位或较小的皮损,缺憾是所需治疗次数多,费用较高.

Objective To evaluate the clinical efficacy of 5-aminolevulinic acid-induced photodynamic therapy （ALA-PDT） in the treatment of condyloma acuminatum. Methods Thirty-six cases of condyloma acuminatum were treated with ALA-PDT. Results After the treatment, 33 （91.67%） patients were cured, 35 （97.22%） improved. Relapse occurred in 3 （8.33%） patients. Side effects were noted in 2 （5.56%） patients. Conclusions ALA-PDT is a relatively simple, effective and safe treatment with a lower recurrence rate for condyloma acuminatum, especially for small skin lesions or lesions at specific area. However, the high expense required for multiple treatments with ALA-PDT may restrict its application.