眩晕定颗粒的吸湿性研究

Study on the Hygroscopicity of Xuanyunding Granule

目的:研究眩晕定颗粒的吸湿性,确定眩晕定颗粒生产过程中合理的湿度条件及暴露时间。方法:通过测定眩晕定颗粒的吸湿速度及平衡吸湿量,建立其动力学模型,提取吸湿速度参数并比较大小。结果:眩晕定颗粒在不同湿度下的吸湿动力学符合房室模型,吸湿量达到6%对应的相对湿度为56.11%,在此湿度下包装前最久可摆放10.15h。结论:眩晕定颗粒生产中应控制环境湿度在56%以下,分装时暴露时间不可超过10.15h。

OBJECTIVE： To study the hygroscopicity of Xuanyunding granule, and to determine reasonable conditions of humidity and exposure time in the production process. METHODS： Dynamics model was established by determining hygroscopic rate and balance moisture absorption volume of Xuanyunding granule. Hydroscopicity rates were determined and compared. RESULTS： Hygroscopicity dynamic equations of Xuanyunding granule at different humidity condition was in line with the compartment model. When absorption capacity reached 6%, relative humidity was 56.11%. Under above condtion, Xuanyunding granule could be stored for 10.15 h at most before packaging. CONCLUSION： In the production process of Xuanyunding granule, humidity should be below 56%, exposure time must be not more than 10.15 hours in packaging process.