基因多态性与中医药防治艾滋病研究

Genetic polymorphism and study on prevention and treatment of AIDS with Chinese medicine

对影响艾滋病进展的相关基因研究成果进行简要介绍,主要包括趋化因子受体/趋化因子受体配体和人类白细胞抗原的基因多态性及其他胞内因子;进而从研究的复杂性和潜在融合性方面阐述了基因多态性与中医药的内在关联,认为中医证候理论可以从宏观表现层面与西医诊断互补,运用基因组学技术将有望实现中西医学思维的融合,在中医药干预艾滋病的诊断与治疗中发挥作用。

The paper introduced briefly the research on relevant genes correlated to AIDS development,including chemokine receptor/chemokine receptor ligands,genetic polymorphism of human leukocyte antigens（HLA） and other intracellular factors.The internal relationship between genetic polymorphism and TCM was interpreted from the aspects of complexity and potential integrative of the research.The author believed that the TCM theory of syndrome manifestations and diagnosis of Western medicine could complement each other at a macroscopic level.The application of genomics technology will help to integrate the thinking of Chinese and Western medicine,and take part in the diagnosis and treatment of AIDS with TCM.