雏鹅钙磷缺乏症的病理学研究

PATHOLOGICALSTUDIESONCALCIUMANDPHOSPHORUSDEFICIENCYINGEESE

１日龄天府肉鹅健雏６０只，随机分３组，分别喂给缺钙（Ｃａ０１５％，ＡＰ０４１％）、缺磷（Ｃａ１０２％，ＡＰ０１７％）和正常对照（Ｃａ１０５％，ＡＰ０４１％）日粮４周。缺钙组病变表现为肋骨质软、骨干内表面出现佝偻珠；胫骨骺生长板之增生带轻度增宽，干骺端类骨组织和疏松结缔组织轻度增生；血清钙含量下降。缺磷组病变表现为肋骨与翅部长骨质软易弯；胫骨骺生长板之肥大带轻度增宽，干骺端类骨组织轻度增生；血清磷含量明显降低。两组发病雏鹅血清碱性磷酸酶活性异常升高和胫骨灰分、灰分钙磷含量明显降低。结果表明，缺钙和缺磷所致病变与血清钙磷含量变化显著不同。

SixtydayoldTianfugeeseweredividedintothreegroups,andfedondietsasfollow:1Cadeficient(Ca015%,AP041%),2Pdeficient(Ca102%,AP017%)and3controls(Ca105%,AP041%)forfourweeksIngroup1,smallbeadingswerepresentontheinnersurfaceoftheribswhichweresoftatnecropsyTheproliferatingzoneofthegrowthplateintheepiphysisoftibiaswaslightlywidenedandirregularOsteoid,looseconnectivetissueproliferatedmildlyinthemetaphysealspongiosahistopathologicallyTheserumCaconcentrationdecreasedGroup2showedadecreasedserumPconcentration,andalightlywidenedhypertrophiczoneofthegrowthplateandaincreasedosteoidtissueinmetaphysealspongiosaoftibiasThelongbonesofwingsandribsweresoftgrosslyTheserumalkalinephosphataseactivitiesweremuchhingher,andtibialash,ashCaandPcontentsmuchloweringroups1and2thanthoseinthecontrolgroupResultsdemonstratedthatthelesionsandchangesoftheserumCaandPconcentrationsproducedbyCadeficiencywereverydifferentfromthoseofPdeficiency