摘要
本文对鸡贫血病毒(CAV)感染新城疫(ND)免疫雏鸡经新城疫强毒(vNDV)攻击后,其血清、泪液、气管液、肠液、胆汁的IgG、IgM、IgA含量和HI抗体滴度;胸腺、法氏囊、脾脏、哈德尔腺、盲肠扁桃体的T细胞,IgG、IgM、IgA抗体生成细胞数量以及免疫保护情况进行了检测。结果发现,CAV感染ND免疫雏鸡经vNDV攻击后,上述体液的IgG、IgM、IgA含量和血清HI抗体滴度均明显低于未感染CAV的免疫对照雏鸡;胸腺、脾脏和盲肠扁桃体的T细胞也明显减少;法氏囊、脾脏、盲肠扁桃体、哈德尔腺的IgG、IgM、IgA抗体生成细胞均程度不同地低于相应的对照雏鸡,其中IgG生成细胞CAV感染雏鸡减少最明显,感染雏鸡的免疫保护率也明显降低。
TheexperimentwasundertakentodetectthecontentofIgG,IgM,IgAandtiterofHIinserum,tear,trachealfluid,intestinalfluidandbile,thenumberofIgG,IgM,andIgAantibodyproducingcellsandTcellinthymus,bursaFabricius,spleen,cecaltonsilandHarderianglandandtheimmuneprotectiveefficacypostvNDVchallengeofCAVinfectedchicksimmunizedwithNDvaccineTheresultsshowedthatafterchallengewithvNDV,thecontentofIgG,IgM,IgAsignificantlydecreasedintheserum,tear,trachealfluid,intestinalfluid,bileofCAVinfectedchicksimmunizedwithNDvaccineincomparisonwiththoseoftheCAVuninfectedcontrolchicks,thetiterofHIofCAVinfectedbirdsimmunizedwithNDvaccinewasalsomarkedlylowerthanthoseofCAVuninfectedcontrolgroupintheserum,thenumberofTlymphocyte,IgG,IgM,IgAantibodyproducingcellsinthementionedaboveimmuneorgansofCAVinfectedbirdsimmunizedwithNDvaccine,toadifferentdegreerespectively,werelessthanthoseofthecontrolchicksTheimmuneprotectiveefficacyofCAVinfectedbirdsimmunizedwithNDvaccinewasmarkedlylowerthanthoseofCAVuninfectedcontrolgroup
出处
《畜牧兽医学报》
CAS
CSCD
北大核心
1999年第3期273-278,共6页
ACTA VETERINARIA ET ZOOTECHNICA SINICA
基金
黑龙江省自然科学基金
东北农业大学联合资助