早期妊娠妇女宫颈糜烂与宫颈炎症关系的分析

The relationship between cervical erosion and cervical inflammation in early pregnant women

目的:探讨早孕妇女宫颈糜烂与宫颈炎症之间的关系。方法:对早孕妇女阴道分泌物进行湿片检查,清洁度Ⅰ～Ⅱ度者,取宫颈管分泌物,行革兰氏染色。显微镜下观察每高倍视野中性粒细胞数和细菌种类。结果:126例早孕妇女中,宫颈分泌物中性粒细胞>30个/高倍视野共23例,其中在宫颈光滑、轻、中和重度糜烂的各组中检出率分别为17.6%(6/34),22.6%(7/31),15.1%(5/33)和17.9%(5/28),各组间差异无统计学意义(χ2=0.613,P(0.05)。宫颈分泌物检出革兰氏阴性杆菌42例,占33.3%(42/126),在宫颈光滑、轻、中和重度糜烂各组间分别占23.5%(8/34),32.3%(10/31),36.4%(12/33)和42.9%(12/28)。检出革兰氏阳性杆菌者53例,其中在宫颈光滑、轻、中和重度糜烂各组间分别为52.9%(18/34),38.7%(12/31),39.4%(13/33)和35.7%(10/28)。检出革兰氏阳性球菌者24例,在宫颈光滑、轻、中和重度糜烂各组间分别为17.6%(6/34),22.6%(7/31),27.3%(9/33)和7.14%(2/28)。各组中无一例检查出革兰氏阴性球菌。比较各组细菌种类,差异无统计学意义(χ2值分别为2.77,2.35,和7.56,P(0.05)。结论:宫颈糜烂程度与宫颈分泌物白细胞增多及细菌种类无相关性,早孕妇女的宫颈糜烂并非是宫颈炎症所致。

Objective：To investigate the relationship between cervical erosion and cervical inflammation in early pregnant women. Methods：The cervical secretions taken from the women with normal vaginal discharge were observed for neutrophil count and bacteria classification by Gram stain. Results：Among 126 normal early pregnant women,23 women had more than 30 neutrophil per power field in cervical secretions. Six women （17.6%） were cervical smooth,and 7 women （22.6%） with mild cervical erosion,5 women （15.1%） with moderate cervical erosion,5 women （17.9%） with severe cervical erosion （χ2=0.613,P0.05）. In 42 women （33.3%） with cervical secretions positive for gram-negative bacilli,8 women （23.5%） were found in cervical smooth group,10 women （32.3%）with mild cervical erosion,12 women （36.4%） with moderate cervical erosion,12 women （42.9%） with severe cervical erosion. In 53 women with positive for gram-positive bacteria,18 women （52.9%） were found in cervical smooth group,12 women （38.7%） with mild cervical erosion,13 women （39.4%） with moderate cervical erosion,10 women （35.7%） with cervical severe erosion. In the women with gram-positive cocci,6 women （17.6%） were found in cervical smooth group,7 women （22.6%） with mild cervical erosion,9 women （27.3%） with moderate cervical erosion,2 women （7.14%） with severe cervical erosion. No women with gram-negative cocci were found in these groups. There were no significant differences in the types of bacteria among these groups （χ2=2.77,2.35,7.56,respectively,P0.05）. Conclusion：There is no relationship between cervical erosion and cervical inflammation. The data in this study suggests that cervical erosion was not caused by cervical inflammation in early pregnant women.