胃镜下注射肾上腺素联合钛夹治疗急性非静脉曲张上消化道出血

Analysis of the curative effect of adrenaline injection combined with titanium clips by gastroendoscopy for acute nonvariceal upper gastrointestinal bleeding

目的 评价胃镜下钛夹和注射肾上腺素联合钛夹的方法治疗急性非静脉曲张上消化道出血的疗效.方法 经胃镜检查确诊为急性非静脉曲张上消化道出血患者65例,随机分为钛夹组（31例）、注射肾上腺素联合钛夹组（注射联合钛夹组,34例）,对出血灶进行治疗,评价两种治疗方法的止血率和再出血率的差异.结果 注射联合钛夹组和钛夹组的所有患者均首次止血成功,止血率均为l00%;钛夹组有6例发生再次出血,再出血率19.4%,注射联合钛夹组中有1例发生再出血,再出血率2.9%,两组差异有统计学意义（P＜0.05）.结论 胃镜下注射肾上腺素联合钛夹治疗非静脉曲张上消化道出血疗效可靠,优于单纯钛夹治疗.

Objective To evaluate the curative effect of titanium clips and adrenaline injection by gastroen-doscopy for acute nonvariceal upper gastrointestinal bleeding （ ANVUGIB）. Methods 65 patients with ANVUGIB were randomly divided into group of titanium clips（31 cases） and group of injection combined with titanium clips（34 cases） for treatment of bleeding. The rate of curative effect of hemostatic and rehaemorrhagia was compared. Results All the patients of the two groups were succeed at the first time hematischesis, the hemostatic rates were all 100%. The titanium clips group has 6 cases rebleeding,and the rehaemorrhagia rate was 19.4% ,the injection combined with titanium clips group has 1 case rebleeding, and the rehaemorrhagia rate was 2. 9%. There was significant difference between the two groups. Conclusions The curative effect of injection with titanium clips was reliable, and was superior to treatment with titanium clips alone.