阿司匹林对糖尿病足溃疡治愈后心脑血管事件发生率的影响

Influence of Aspirin to the incidence of cardiovascular and cerebrovascular events after healing of diabetic foot ulcer

目的 探讨阿司匹林对糖尿病足溃疡愈合后心脑血管事件发生率的影响.方法 对54例糖尿病足溃疡患者治愈后跟踪随访,根据是否续用阿司匹林,分两组观察其1年、3年、5年后心脑血管事件发生率.结果 两组心脑血管事件发生率差异有统计学意义（P＜0.01）,且未续用阿司匹林组1年后发生心脑血管事件增加显著.结论 阿司匹林对预防糖尿病足溃疡后心脑血管的发生有重要意义.

Objective To explore the influence of Aspirin to the incidence of cardiovascular and cerebrovas-cular events after healing of diabetic foot ulcer. Methods 54 patients with diabetic foot ulcer were followed up after cure. Depending on whether continued use of Aspirin,54 cases were divided into two groups and observed 1 year,3 years,5 years later. Then the incidence of cardiovascular and cerebrovascular events were compared between two groups. Results The incidence of cardiovascular and cerebrovascular events were significantly different between two groups（P〈0. 05） ,and it increased significantly in the group which were not continued with Aspirin after 1-year. Conclusion Aspirin playedan important role in preventing incidence of cardiovascular and cerebrovascula events after healing of diabetic foot ulcer.